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Structural and conformational analysis of spiro(1,3-dithiolane-2,3′-indolin)-2′-one: An anticonvulsant analog

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Abstract

The structure was solved by the heavy-atom method, and refined by full-matrix least squares to anR value of 0.037 for 1670 observed reflections. The bond linking the amide to the tetrahedral carbon atom is a single bond. The six-membered ring is perfectly planar, whereas the five-membered ring deviates from planarity. The five- and six-membered rings are inclined to one another at 2.6(1)°, and the dithiolane ring is nearly perpendicular to the indolinone group.

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Author notes

  1. Amitabha De

    Present address: Structural Studies Division, MRC Laboratory of Molecular Biology, Hills Road, CB2 2QH, Cambridge, England

Authors and Affiliations

  1. Department of Physics, University College of Science, 92, Acharya Prafulla Chandra Road, 700 009, Calcutta, India

    Amitabha De

  2. Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, 565, Osaka, Japan

    Masami Kusunoki

Authors
  1. Amitabha De
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  2. Masami Kusunoki
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De, A., Kusunoki, M. Structural and conformational analysis of spiro(1,3-dithiolane-2,3′-indolin)-2′-one: An anticonvulsant analog. Journal of Crystallographic and Spectroscopic Research 21, 57–60 (1991). https://doi.org/10.1007/BF01158975

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  • DOI: https://doi.org/10.1007/BF01158975

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