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Control of fibroblast activity in scars: a review

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Abstract

Fibroblasts in healing wounds are activated by cytokines secreted by cells at the wound site, especially macrophages and T-lymphocytes-paracrine mechanism. Biochemical control of fibroblast activity is most likely to be activated by inhibiting these cells or by neutralizing their cytokines. TGFβ is the most likely target.

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Authors and Affiliations

  1. Department of Plastic and Reconstructive Surgery, Aberdeen Royal Hospitals, AB9 2ZB, Aberdeen, Foresterhill, UK

    I. F. K. Muir

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  1. I. F. K. Muir
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Muir, I.F.K. Control of fibroblast activity in scars: a review. Eur J Plast Surg 21, 1–7 (1998). https://doi.org/10.1007/BF01152415

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  • DOI: https://doi.org/10.1007/BF01152415

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