Conclusions
-
1.
The level of type-II glucocorticoid receptors in cytosol of various tissues is characterized by the following decreasing sequence: liver, kidneys, heart, lungs.
-
2.
Dissociation constants of the glucocorticoid receptor-T-AC complex in cytosol of the lvier, kidneys, heart, and lungs fluctuated unsubstantially: from 0.77·10−8 to 1.1·10−8 M.
Similar content being viewed by others
Literature cited
J. D. Baxter and P. H. Forsham, Am. J. Med.,53, 573–589 (1972).
M. Beato and F. H. Feigelson, J. Biol. Chem.,247, 7890–7896 (1972).
D. Feldman and J. W. Runder, Endocrinology,92, 1429–1436 (1973).
T. Murakami, J. Steroid Biochem.,10, 475–481 (1979).
D. W. Keller, J. Clin. Endocrinol.,48, 127–132 (1979).
G. Scatchard, Ann. N. Y. Acad. Sci.,51, 660–665 (1979).
O. H. Lowry et al., J. Biol. Chem.,193, 265–274 (1951).
M. K. Agarwal, Biochem. Med.,17, 193–201 (1977).
J. W. Funder, D. Duval, and P. H. Mayer, Endocrinology,93, 1300–1308 (1973).
M. C. Gregory, D. Duval, and P. Meyer, Clin. Sci. Mol. Med.,51, 487–493 (1976).
A. Boer, Biochim. Biophys. Acta,586, 70–86 (1979).
N. M. Seleznev, S. M. Danilov, A. A. Shnyra, et al., Biokhimiya, No. 11, 1984–1995 (1981).
N. M. Bortwick and P. A. Bell, Mol. Cell. Endocrinol.,9, 269–278 (1978).
F. Homo and D. Duval, J. Steroid Biochem.,13, 135–143 (1980).
J. A. Gidlowski and J. W. Thanassi, J. Steroid Biochem.,15, 11–16 (1981).
R. D. Markovic and H. J. Eisen, Biochemistry,19, 4556–4564 (1980).
Seikichi Tsuboi, Brain Res.,179, 181–185 (1979).
G. Giannopoulos, Endocrinology,94, 450–458 (1974).
F. Svec and M. Rudis, Biochim. Biophys. Acta,674, 215–219 (1980).
M. Lindenbaum and R. T. Chatterton, Endocrinology,109, 363–375 (1981).
D. Feldman, Endocrinology,103, 2091–2096 (1978).
H. Bojar and S. Westerkamp, Hepato-Gastroenterol.,27, 176–182 (1981).
Author information
Authors and Affiliations
Additional information
Deceased.
Translated from Problemy Éndokrinologii, Vol. 30, No. 6, pp. 43–45, November–December, 1984.
Rights and permissions
About this article
Cite this article
Golikov, P.P., Nikolaeva, N.Y. Status of type-II glucocorticoid receptors in tissues of adrenalectomized rats. Neurosci Behav Physiol 16, 289–291 (1986). https://doi.org/10.1007/BF01148169
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01148169