Conclusions
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1.
The ionic mechanisms of the plasticity of two types of neurons in the brain of the edible snail: habituating (HC) and nonhabituating (NHC), to rhythmic intracellular stimulation were investigated.
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2.
It was shown that the development of habituation of HC is due to the entrance of Ca2+ into the cell and its activation of the Ca-dependent K-conductivity of the membrane, resulting in hyperpolarization, a decrease in Rin, and turnoff of the spike response to stimulation. Suppression of the Ca2+-dependent K-conductivity by quinine entirely blocks the ability of the HC for habituation.
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3.
The data obtained on NHC are evidence that their nonhabituation to intracellular stimulation is a result of the absence of weak expression of the Ca-dependent K-conductivity in their membrane. After entering the cell, Ca2+ can have a depolarizing effect upon stimulation of the electrical activity of the NHC and can cause effects of facilitation, i.e., increase the responses to stimulation.
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Translated from Zhurnal Vysshei Nervnoi Deyatel'nosti imeni I. P. Pavlova, Vol. 35, No. 3, pp. 552–560, May–June, 1985.
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D'yakonova, T.L. Two types of neurons differing in plastic properties: Study of ionic mechanisms. Neurosci Behav Physiol 16, 277–284 (1986). https://doi.org/10.1007/BF01148167
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DOI: https://doi.org/10.1007/BF01148167