Skip to main content
Log in

A model to show human uterine receptivity and embryo viability following ovarian stimulation for in vitro fertilization

  • Special Contributions
  • Published:
Journal of in Vitro Fertilization and Embryo Transfer Aims and scope Submit manuscript


A comparison of the implantation rates following in vitro fertilization (IVF) and embryo transfer (ET) for four major groups indicates differences in the implantation rates as well as in the incidence of multiple implantation. By assuming that the probability of implantation is the product of two variables, uterine receptivity (U) and embryo viability (E), estimates for U and E are derived for each of the four (VF groups using maximum likelihood methods. The UE model is tested using chi-squared goodness-of-fit methods for predicted implantation rates versus observed. The possibility that differences in U values between groups are due to different ovarian stimulation protocols is discussed, as is the values of the UE model in highlighting differences between IVF groups and its importance in predicting multiple pregnancy rates.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others


  1. Trounson A, Wood C: IVF results 1979–1982 at Monash University-Queen Victoria-Epworth Medical Centre. Vitro Fert Embryo Transfer 1984;1:42–47

    Google Scholar 

  2. Jones HW, Acosta AA, Andrews MC, Garcia JE, Jones GS, Mayer J, McDowell JS, Rosenwaks Z, Sandow BA, Veeck LL, Wilkes CA: Three years of in vitro fertilization at Norfolk. Ferti Steril 1984;42:826–834

    Google Scholar 

  3. Lopata A: Concepts in human in vitro fertilization and embryo transfer. Fertil Steril 1983;40:289–301

    PubMed  Google Scholar 

  4. Edwards RG, Steptoe PC: Current status of in-vitro fertilization and implantation of human embryos. Lancet. 1983;8362:1265–1269

    Google Scholar 

  5. Speirs AL, Lopata A, Gronow MJ, Kellow GN, Johnston WIH: Analysis of the benefits and risks of multiple embryo transfer. Fertil Steril 1983;39:468–471

    PubMed  Google Scholar 

  6. Jones HW, Acosta AA, Andrews MC, Garcia JE, Jones GS, Mantzavinos T, McDowell J, Sandow BA, Veeck L, Whibley TW, Wilkes CA, Wright GL: What is a pregnancy? A question for programs of in vitro fertilization Fortil Steril 1983;40:728–733

    Google Scholar 

  7. Trounson A, Caro CM, Jessup D: The effect of maternal age of the success rate of in vitro fertilization (IVF). Aust Soc Rep Biol, Proc 16th Annu Conf, 1984, p 55 (abstr)

  8. Kokko E, Janne O, Kauppila A, Vihko R: Cyclic clomiphene citrate treatment lowers cytozol estrogen and progestin receptor concentrations in the endometrium of post menopausal women on estrogen replacement therapy. J Clin Endocrinol Metab 1981;52:345–349

    PubMed  Google Scholar 

  9. Edwards RG, Fishel SB, Cohen J, Fehilly CB, Purdy JM, Slater JM, Steptoe PC, Webster JM: Factors influencing the success of in vitro fertilization for alleviating human infertility. J Vitro Fert Embryo Transfer 1984;1:3–23

    Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and permissions

About this article

Cite this article

Rogers, P.A.W., Milne, B.J. & Trounson, A.O. A model to show human uterine receptivity and embryo viability following ovarian stimulation for in vitro fertilization. J Assist Reprod Genet 3, 93–98 (1986).

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI:

Key Words