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Diagnostic value of transesophageal echocardiography in atrial septal aneurysm

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Abstract

Transthoracic and transesophageal echocardiography was performed in 40 consecutive adult patients with an atrial septal aneurysm. In 11 (27%) of 40 patients transthoracic echocardiography failed to demonstrate the lesion and the diagnosis was established by the transesophageal approach only. Interatrial shunting, assessed by echocardiographic contrast study and/or color flow mapping, was detected in 13 (54%) of 24 patients on transthoracic imaging and in 29 (76%) of 38 patients during transesophageal echocardiography. Identification of multiple fenestrations (n=9) and thrombi within the aneurysm (n=2) could be achieved only by transesophageal ultrasound. A cerebrovascular event of suspected embolic origin occurred in 20 (50%) of 40 patients; 11 (55%) of the 20 patients had repeated cerebral events. Except for mitral valve prolapse in 2 patients and spontaneous left atrial contrast phenomenon in 1 patient no other potential cardiac source of embolism could be identified by transesophageal echocardiography. A marked thickening of the aneurysm was present in 14 (70%) of 20 patients with a cerebrovascular event versus only 4 (20%) of 20 patients without a cerebrovascular event (p<0,01). The mechanism of embolization may be both primary thrombus formation within the aneurysm and paradoxical embolization through an interatrial communication as suggested by the findings on transesophageal ultrasound in 2 patients. Although the patients of this study represent a highly selected group it may be concluded that atrial septal aneurysm is a cardiac abnormality with embolic potential. Transesophageal echocardiography has to be regarded the imaging method of choice for evaluation of this lesion.

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References

  1. Lang FJ, Posselt A. Aneurysmatische Vorwölbung der Fossa ovalis in den linken Vorhof. Wien Med Wochenschr 1934; 84: 392–5.

    Google Scholar 

  2. Lev M, Saphir O. Congenital aneurysm of the membranous septum. Arch Pathol 1938; 25: 819–37.

    Google Scholar 

  3. Schwarz E. Aneurysmatische Aussackung der Vorhofscheidewand des Herzens. Zentralbl Allg Pathol 1964; 106: 249–51.

    Google Scholar 

  4. Silver MD, Dorsey JS. Aneurysms of the septum primum in adults. Arch Pathol Lab Med 1978; 102: 62–5.

    Google Scholar 

  5. Thompson JI, Phillips LA, Melmon KL. Pseudotumor of the right atrium: Report of a case and review of its etiology. Ann Intern Med 1966; 64: 665–7.

    Google Scholar 

  6. Grosgogeat Y, Lhermitte F, Carpentier A, Facquet J, Alhomme P, Tran TX. Anevrysme de la cloison interauriculaire revele par une embolie cerebrale. Arch Mal Coeur 1973; 66: 169–77.

    Google Scholar 

  7. Freedom RM, Rowe RD. Aneurysm of the atrial septum in tricuspid atresia: Diagnosis during life and therapy. Am J Cardiol 1976; 38: 265–7.

    Google Scholar 

  8. Gerard R, Baille Y, Luccioni R, Gatau-Pelanchon J, Duport G. Anevrisme du septum inter-auriculaire et valvulopathie mitrale. Coeur 1979; 10: 579–86.

    Google Scholar 

  9. Sahn DJ, Allen HD, Anderson R, Goldberg SJ. Echocardiographic diagnosis of atrial septal aneurysm in an infant with hypoplastic right heart syndrome. Chest 1978; 73: 227–30.

    Google Scholar 

  10. Alexander MD, Bloom KR, Hart P, D'Silva F, Murgo J. Atrial septal aneurysm: A cause for midsystolic click: Report of a case and review of the literature. Circulation 1981; 63: 1186–8.

    Google Scholar 

  11. Gondi B, Nanda NC. Two-dimensional echocardiographic features of atrial septal aneurysms. Circulation 1981; 63: 452–7.

    Google Scholar 

  12. Hauser AM, Timmis GC, Stewart JR, et al. Aneurysm of the atrial septum as diagnosed by echocardiography: Analysis of 11 patients. Am J Cardiol 1984; 53: 1401–2.

    Google Scholar 

  13. Iliceto S, Papa A, Sorino M, Rizzon P. Combined atrial septal aneurysm and mitral valve prolapse: Detection by two-dimensional echocardiography. Am J Cardiol 1984; 54: 1151–3.

    Google Scholar 

  14. Longhini C, Brunazzi MC, Musacci G, et al. Atrial septal aneurysm: Echopolycardiographic study. Am J Cardiol 1985; 56: 653–6.

    Google Scholar 

  15. Hanley PC, Tajik AJ, Hynes JK, et al. Diagnosis and classification of atrial septal aneurysm by two-dimensional echocardiography: Report of 80 consecutive cases. J Am Coll Cardiol 1985; 56: 653–6.

    Google Scholar 

  16. Schreiner G, Erbel R, Mohr-Kahaly S, Krämer G, Henkel B, Meyer J. Nachweis von Aneurysmen des Vorhofseptums mit Hilfe der transösophagealen Echokardiographie. Z Kardiol 1985; 6: 1370–82.

    Google Scholar 

  17. Belkin RN, Waugh RA, Kisslo J. Interatrial shunting in atrial septal aneurysm. Am J Cardiol 1986; 57: 310–2.

    Google Scholar 

  18. Gallet B, Malergue MC, Adams C, et al. Atrial septal aneurysm, a potential cause of systemic embolism: An echocardiographic study. Br Heart J 1985; 53: 292–7.

    Google Scholar 

  19. Belkin RN, Hurwitz BJ, Kisslo J. Atrial septal aneurysm: Association with cerebrovascular and peripheral embolic events. Stroke 1987; 18: 856–62.

    Google Scholar 

  20. Zenker G, Erbel R, Krämer G, et al. Transesophageal two-dimensional echocardiography in young patients with cerebral ischemic events. Stroke 1988; 19: 345–8.

    Google Scholar 

  21. Hanrath P, Schlüter M, Langenstein BA, et al. Detection of ostium secundum atrial septal defects by transesophageal cross-sectional echocardiography. Br Heart J 1983; 49: 350–8.

    Google Scholar 

  22. Daniel WG, Nellessen U, Schröder E, et al. Left atrial spontaneous echo contrast in mitral valve disease: An indicator for an increased thromboembolic risk. J Am Coll Cardiol 1988; 11: 1204–11.

    Google Scholar 

  23. Mikell FL, Asinger RW, Elsberger J, Anderson WR, Hodges M. Regional stasis of blood in dysfunctional left ventricle: Echocardiographic detection and differentiation from early thrombosis. Circulation 1982; 66: 755–63.

    Google Scholar 

  24. Cerebral Embolism Task Force. Cardiogenic brain embolism. The second report of the cerebral embolism task force. Arch Neurol 1989; 46: 727–43.

    Google Scholar 

  25. Ringelstein EB, Zeumer H, Schneider R. Der Beitrag der zerebralen Computertomographie zur Differentialtypologie des ischämischen Gro\hirninfarktes. Fortschr Neurol Psychiat 1985; 53: 315–36.

    Google Scholar 

  26. Brown JJ, Hesslink JR, Rothrock JF. MR and CT of lacunar infarets. Am J Radiol 1988; 151: 367–72.

    Google Scholar 

  27. Santamaria J, Graus F, Rubio F, Arbizu T, Peres J. Cerebral infarction of the basal ganglia due to embolism from the heart. Stroke 1983; 14: 911–4.

    Google Scholar 

  28. Roberts WC. Aneurysm (redundancy) of the atrial septum (fossa ovale membrane) and prolapse (redundancy) of the mitral valve. Am J Cardiol 1984; 54: 1153–4.

    Google Scholar 

  29. Forfar JC, Godman MJ. Functional and anatomic correlates in atrial septal defect: An echocardiographic analysis. Br Heart J 1985; 54: 193–200.

    Google Scholar 

  30. Greenland P, Knopman DS, Mikell FL, Asinger RW, Anderson DC, Good DC. Echocardiography in diagnostic assessment of stroke. Ann Intern Med 1981; 95: 51–3.

    Google Scholar 

  31. Lovett JL, Sandok BA, Giuliani ER, Nasser FN. Two-dimensional echocardiography in patients with focal cerebral ischemia. Ann Intern Med 1981; 95: 1–4.

    Google Scholar 

  32. Donaldson RM, Emanuel RW, Earl CJ. The role of two-dimensional echocardiography in the detection of potentially embolic intracardiac masses in patients with cerebral ischemia. J Neurol Neurosurg Psychiat 1981; 44: 803–9.

    Google Scholar 

  33. Pearson AC, Labovitz AJ, Tatineni S, Gomez CR. Superiority of transesophageal echocardiography in detecting cardiac source of embolism in patients with cerebral ischemia of uncertain etiology. J Am Coll Cardiol 1991; 17: 66–72.

    Google Scholar 

  34. Hofmann T, Kasper W, Meinertz T, Geibel A, Just H. Echocardiographic evaluation of patients with clinically suspected arterial emboli. Lancet 1990; 336: 1421–24.

    Google Scholar 

  35. Abinader EG, Rokey R, Goldhammer E, Kuo LC, Said E. Prevalence of atrial septal aneurysm in patients with mitral valve prolapse. Am J Cardiol 1988; 62: 1139–40.

    Google Scholar 

  36. Rahko PS, Yu QB. Increased prevalence of atrial septal aneurysm in mitral valve prolapse. Am J Cardiol 1990; 66: 235–7.

    Google Scholar 

  37. Chesler E, King RA, Edwards JE. The myxomatous mitral valve and sudden death. Circulation 1983; 67: 632–9.

    Google Scholar 

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Schneider, B., Hofmann, T., Meinertz, T. et al. Diagnostic value of transesophageal echocardiography in atrial septal aneurysm. Int J Cardiac Imag 8, 143–152 (1992). https://doi.org/10.1007/BF01137535

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