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Synthesis of poly-L-arginine and the statistical copolymer of L-arginine, L-lysine, and neutral amino acids

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Chemistry of Natural Compounds Aims and scope

Summary

1. A method for the quantitative guanidation of the Nδ-amino groups of ornithine in polypeptides has been developed. By means of this method poly-L-arginine with a high molecular weight (about 88 000) has been obtained for the first time.

2. A statistical copolymer simultaneously including L-arginine and L-lysine residues has been synthesized for the first time.

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Authors and Affiliations

  1. Zelinskii Institute of Organic Chemistry, AS USSR, USSR

    V. G. Debabov, V. D. Davydov & Yu. N. Kosaganov

Authors
  1. V. G. Debabov
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  2. V. D. Davydov
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  3. Yu. N. Kosaganov
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Additional information

Khimiya Prirodnykh Soedinenii, Vol. 2, No. 3, pp. 195–200, 1966

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Debabov, V.G., Davydov, V.D. & Kosaganov, Y.N. Synthesis of poly-L-arginine and the statistical copolymer of L-arginine, L-lysine, and neutral amino acids. Chem Nat Compd 2, 156–160 (1966). https://doi.org/10.1007/BF01134237

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  • DOI: https://doi.org/10.1007/BF01134237

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