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An improved synthesis of 1,1,1-trichloro-2-methyl-2-propanol (chlorobutanol)

Eine verbesserte Synthese von 1,1,1-Trichlor-2-methyl-2-propanol (Chlorbutanol) (Kurze Mitteilung)

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  • Organische Chemie Und Biochemie
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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Abstract

Varying reaction time, temperature, and the amount of catalyst and reactants the synthesis of chlorobutanol from chloroform and acetone with KOH as catalyst is optimized to 71% yield.

Zusammenfassung

Es wird die Synthese von Chlorbutanol aus Chloroform und Aceton mit KOH als Katalysator bezüglich Reaktionszeit, Reaktionstemperatur, Katalysatormenge und Verhältnis der eingesetzten Reaktanten auf 71% Ausbeute optimiert.

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Authors and Affiliations

  1. School of Pharmaceutical Sciences, Isfahan University, Isfahan, Iran

    M. Saljoughian, A. Raisi, E. Alipour & S. Afshar

Authors
  1. M. Saljoughian
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  2. A. Raisi
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  3. E. Alipour
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  4. S. Afshar
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Saljoughian, M., Raisi, A., Alipour, E. et al. An improved synthesis of 1,1,1-trichloro-2-methyl-2-propanol (chlorobutanol). Monatsh Chem 114, 813–816 (1983). https://doi.org/10.1007/BF01134193

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  • DOI: https://doi.org/10.1007/BF01134193

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