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Role of ribonucleic acid in preservation of temporary connections

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Conclusions

Ribonuclease, injected directly into the brain through permanently implanted cannulas, causes reversible loss of conditioned reflexes. This was observed in 80% of experiments with injection into the hippocampus, in 17.7% with injection into the motor cortex, and in 20% of experiments with injection into the visual cortex.

Control injection of physiological saline and serum albumin into these structures did not disturb conditioned-reflex activity.

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References

  1. GERMANYUK, Ya. L. Vop. Med. Khim. 11:34, 1963.

    Google Scholar 

  2. D'YAKONOVA, T. L., B. N. VEPRINTSEV A. F. CHAPAS and V. Ya. BRODSKII. Biofizika. 10:826, 1965. (Translation published in Federation Proceedings, Part II, Translation Supplement. 25(5):T901–T904, 1966.)

    Google Scholar 

  3. ZAGUSKIN, S. L. Tsitologiya. 6:741, 1964.

    Google Scholar 

  4. KIKNADZE, I. I. and FILATOVA, I. T. Izv. Sib. Otd. Akad. Nauk SSSR. 12:131, 1960.

    Google Scholar 

  5. KOGAN, A. B. and S. L. ZAGUSKIN Zh. Evolyuts. Fiziol. Biokhim. 1:59, 1965. (Translation published in Federation Proceedings, Part II, Translation Supplement. 25(2):T191–T195, 1966).

    Google Scholar 

  6. KOKINA, N. N. Abstracts of Scientific Reports. Moscow State University, 1965, p. 29.

  7. KORSAKOV, S. S. Selected Works. Moscow, 1954.

  8. KOSHTOYANTS, Kh. S. Enzymochemical Processes of Excitation and Inhibition and Evolution of Functions of the Nervous System. Moscow, 1963.

  9. KRYLOV, O. A., R. A. DANILOVA and V. S. TONGUR. Abstracts of Proceedings of the 4th Scientific Conference on Evolutionary Physiology. 1965, p. 161; Usp. Sovrem. Biol. 60:336, 1965; Zh. Vyssh. Nerv. Deyatel'nosti im I. P. Pavlova. 15:79, 1965.

  10. MALINOVSKII, O. V. Fiziol. Zh. SSSR. im I. M. Sechenova. 38:637, 1952.

    Google Scholar 

  11. MEI CHÊN-TUNG Sci. Sinica. 13:524, 1964.

    Google Scholar 

  12. NORTHROP, J. H., M. KUNITZ and R. HERRIOTT. Crystalline Enzymes. Moscow, Foreign Literature Press, 1960.

    Google Scholar 

  13. POLEZHAEV, L. V. Izv. Akad. Nauk SSSR, Ser. Biol. 2:254, 1966.

    Google Scholar 

  14. POPOVA, L. T. Zh. Nevropatol. Psikhiat. im S. S. Korsakova. 64:1515, 1964.

    Google Scholar 

  15. SMIRNOVA, N. A. and S. M. RAPPOPORT. Nauch. Dokl. Vyssh. Shkoly, Ser. Biol. Nauk. 1:42, 1966.

    Google Scholar 

  16. TEPLITS, N. A. Dokl. Akad. Nauk SSSR. 147:244, 1962; Dokl. Akad, Nauk SSSR. 156:1207, 1964; Dokl. Akad. Nauk SSSR. 159:442, 1964.

    Google Scholar 

  17. TUSHMALOVA, N. A. Tr. Inst. Vyssh. Nerv. Deyatel'nosti, Ser. Fiziol 6:203, 1961.

    Google Scholar 

  18. TUSHMALOVA, N. A. Abstracts of Proceedings of the 19th Conference on Higher Nervous Activity, Part 2. 1960, p. 132.

    Google Scholar 

  19. CORNING, W. C. and E. R. JOHN. Science. 134:1363, 1961.

    Google Scholar 

  20. DELAY, J. and S. BRION. Presse Méd. 66:1849, 1958.

    Google Scholar 

  21. GRASTYAN, E. R., K. LISSAK, J. SZABO and G. VEREBY. In: Current Problems in Physiology of the Nervous and Muscular System. Tbilisi, 1956, p. 67.

  22. GRASTYAN, E. R., K. LISSAK, F. KEKESI and J. SZABO. Physiol. Bohemoslov. 7:1, 1958.

    Google Scholar 

  23. KAADA, B. R., W. RASMUSSEN and O. KVEIM Exp. Neurol. 3:4, 1961.

    Google Scholar 

  24. KRYLOV, O. A., R. A. DANILOVA and V. S. TONGUR Life Sci. 4:1313, 1965.

    Google Scholar 

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Authors and Affiliations

  1. Department of Physiology of Higher Nervous Activity, Lomonosov State University, Moscow

    L. G. Voronin, N. A. Tushmalova & I. I. Kazennova

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  1. L. G. Voronin
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  2. N. A. Tushmalova
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  3. I. I. Kazennova
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Voronin, L.G., Tushmalova, N.A. & Kazennova, I.I. Role of ribonucleic acid in preservation of temporary connections. Neurosci Behav Physiol 2, 536–542 (1968). https://doi.org/10.1007/BF01125445

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