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Inhibition of chlorophyll synthesis inHordeum vulgare by 3-amino 2,3-dihydrobenzoic acid (gabaculin)

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Bioscience Reports

Abstract

Gabaculin (3-amino 2,3-dihydrobenzoic acid) is shown to be a very potent inhibitor of chlorophyll formation inHordeum vulgate. Exposure of leaf segments to 30/μM gabaculin results in an 80% inhibition of chlorophyll synthesis, and this is paralleled by a decrease in carotenoid. Dual-inhibitor studies with dioxoheptanoic acid, which is an inhibitor of δ⇐inolaevulinic acid dehydratase, show that gabaculin inhibits an earlier step than dioxoheptanoic acid and affects δ-aminolaevulinic acid synthesis rather than its subsequent metabolism.

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Authors and Affiliations

  1. Department of Biochemistry and Agricultural Biochemistry, The University College of Wales, SY23 3DD, Aberystwyth, Dyfed, UK

    Corinne M. Hill, Sharon A. Pearson, Arnold J. Smith & Lyndon J. Rogers

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  1. Corinne M. Hill
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  2. Sharon A. Pearson
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  3. Arnold J. Smith
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  4. Lyndon J. Rogers
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Hill, C.M., Pearson, S.A., Smith, A.J. et al. Inhibition of chlorophyll synthesis inHordeum vulgare by 3-amino 2,3-dihydrobenzoic acid (gabaculin). Biosci Rep 5, 775–781 (1985). https://doi.org/10.1007/BF01119876

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  • DOI: https://doi.org/10.1007/BF01119876

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