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Inhibition and reversal of denervation-induced atrophy by theβ-agonist growth promoter, clenbuterol

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Bioscience Reports

Abstract

Dietary administration of the growth promoter, clenbuterol, ameliorated denervation-induced atrophy in rat soleus muscles. In acutely denervated muscles the drug inhibited the appearance of atrophy, and in chronically denervated muscles the atrophy was almost fully reversed. Responses in slow twitch oxidative fibres were particularly marked.

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Maltin, C.A., Reeds, P.J., Delday, M.I. et al. Inhibition and reversal of denervation-induced atrophy by theβ-agonist growth promoter, clenbuterol. Biosci Rep 6, 811–818 (1986). https://doi.org/10.1007/BF01117104

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  • DOI: https://doi.org/10.1007/BF01117104

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