Skip to main content
SpringerLink
Log in

Colchicine, colcemide and cytochalasin B do not affect translocation of the glucocorticoid hormone-receptor in rat thymocytes or ehrlich ascites cells

  • Short Papers
  • Published:
Bioscience Reports

Abstract

The involvement of intracellular cytoskeletal elements in the translocation of the dexamethasone-receptor complex from the cytoplasm to the nucleus was studied using the cytoskeleton-disrupting agents colcemide, colchicine and cytochalasin B. These compounds did not affect the translocation of the hormone-receptor complex. We conclude that microfilaments and microtubules do not play a role in the translocation of the glucocorticoid hormone-receptor complex from the cytoplasm to the nucleus.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abbreviations

EAT-cells:

Ehrlich Ascites Tumor Cells

MEM:

Minimum Essential Medium

Author information

Authors and Affiliations

  1. Max-Planck-Institut für Zellbiologie, D-6802, Ladenburg, FRG

    Constantine E. Vorgias, Georg A. Perides & Peter Traub

  2. Center of Biological Research, National Hellenic Research Foundation, Athens, Greece

    Constantine E. Sekeris

Authors
  1. Constantine E. Vorgias
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Georg A. Perides
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Peter Traub
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Constantine E. Sekeris
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vorgias, C.E., Perides, G.A., Traub, P. et al. Colchicine, colcemide and cytochalasin B do not affect translocation of the glucocorticoid hormone-receptor in rat thymocytes or ehrlich ascites cells. Biosci Rep 8, 193–197 (1988). https://doi.org/10.1007/BF01116464

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01116464

Key Words

Search

Navigation