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Purine nucleotide cycle enzymes in dystrophic and normal mouse muscle

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Bioscience Reports

Abstract

A comparative study of the operation of the purine nucleotide cycle and of the activity of adenylosuccinase in extracts of muscle from the two strains of dystrophic mouse shows that the cycle is defective in both cases in the conversion of adenylosuccinate to AMP. However, adenylosuccinase activity is only slightly reduced in the standard conditions for its direct assay.

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Fitt, P.S., Parliament, M.B. Purine nucleotide cycle enzymes in dystrophic and normal mouse muscle. Biosci Rep 2, 177–183 (1982). https://doi.org/10.1007/BF01116381

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  • DOI: https://doi.org/10.1007/BF01116381

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