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Cystine uptake by rat jejunal brushborder membrane vesicles

  • Published:
Bioscience Reports

Abstract

The presence of a sodium-stimulated, saturable uptake process for L-cystine is described in brushborder membrane vesicles isolated from rat jejunal mucosa. Concentration-dependence studies indicate the presence of a single transport system for cystine withK m=0.053 mM andV max=0.633 nmol/mg/15 s. Lysine completely inhibits the uptake of cystine.

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Author notes

  1. Božena Ožegović (Visiting scientist)

    Present address: Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Yugoslavia

Authors and Affiliations

  1. Division of Biochemical Development and Molecular Diseases, Children's Hospital of Philadelphia, Philadelphia, PA, USA

    Božena Ožegović (Visiting scientist), Pamela D. McNamara & Stanton Segal

  2. Departments of Pediatrics and Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA

    Božena Ožegović (Visiting scientist), Pamela D. McNamara & Stanton Segal

Authors
  1. Božena Ožegović
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  2. Pamela D. McNamara
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  3. Stanton Segal
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Ožegović, B., McNamara, P.D. & Segal, S. Cystine uptake by rat jejunal brushborder membrane vesicles. Biosci Rep 2, 913–920 (1982). https://doi.org/10.1007/BF01114898

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  • DOI: https://doi.org/10.1007/BF01114898

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