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Dental enamel matrix: Sequences of two amelogenin polypeptides

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Bioscience Reports

Abstract

The amino acid sequences of a leucine-rich amelogenin polypeptide (LRAP) and a tyrosine-rich amelogenin polypeptide (TRAP), isolated from foetal bovine enamel matrix, were determined. Both LRAP and TRAP occurred in two forms; in each case, one of the molecular species appeared to be shortened at the COOH terminus by 2 and 4 residues, respectively. A striking finding was that LRAP and TRAP had identical sequences for the first 33 residues but were almost completely different for the remaining 12 amino acids.

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Author notes

  1. A. G. Fincham

    Present address: Faculty of Medicine, University of West Indies, Mona, Kingston 7, Jamaica, West Indies

  2. A. B. Belcourt

    Present address: Groupe de Recherches INSERM U 157, Centre de Recherches Odontologiques, Faculté de Chirurgie Dentaire, Université Louis Pasteur, 1 Place de l'Hôpital, 6700, Strasbourg, France

Authors and Affiliations

  1. Skeletal Matrix Biochemistry Section, Laboratory of Biological Structure, National Institute of Dental Research, National Institutes of Health, 20205, Bethesda, Maryland, USA

    A. G. Fincham, A. B. Belcourt & J. D. Termine

  2. Institute of Dental Research, School of Dentistry, University of Alabama in Birmingham, 35294, Birmingham, Alabama, USA

    W. T. Butler & W. C. Cothran

Authors
  1. A. G. Fincham
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  2. A. B. Belcourt
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  3. J. D. Termine
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  4. W. T. Butler
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  5. W. C. Cothran
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Fincham, A.G., Belcourt, A.B., Termine, J.D. et al. Dental enamel matrix: Sequences of two amelogenin polypeptides. Biosci Rep 1, 771–778 (1981). https://doi.org/10.1007/BF01114799

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  • DOI: https://doi.org/10.1007/BF01114799

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