Abstract
Phosphorylation of uridine by heating with inorganic orthophosphates can take place through reaction of nucleoside with thermally produced polyphosphate or direct reaction of nucleoside with orthophosphate or a combination of both. The relative importance of the two pathways varies with the orthophosphate and temperature.
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Beck, A., Lohrmann, R., and Orgel, L. E.: 1967Science 157, 952.
Edwards, J. W. and Herzog, A. H.: 1957,J. Am. Chem. Soc. 79, 3647.
Feldmann, W., 1967,Chem. Ber. 100, 3850.
Fuchs, R. J. and Czeck, F. W., 1963,Anal. Chem. 35, 769.
Hall, R. H. and Khorana, H. G.: 1955,J. Am. Chem. Soc. 77, 1871.
Hill, W. L., Hendricks, S. B., Fox, E. J., and Cady, J. G.: 1947,Ind. Eng. Chem. 38, 1667.
Michelson, A. M.: 1958,J. Chem. Soc. 1957.
Moravek, J.: 1967,Tetahedron Letters, 1707.
Moravek, J. and Skoda, J.: 1967,Coll. Czech. Chem. Comm. 32, 206.
Newesley, H.: 1967,Monat. Chem. 98, 379.
Ponnamperuma, C. and Mack, R.: 1965,Science 148, 1221.
Rabinowitz, J., Chang, S., and Ponnamperuma, C.: 1968a,Nature 157, 442.
Rabinowitz, J., Chang, S., and Ponnamperuma, C.: 1968b,Proteins and Nucleic Acids Symposium: Synthesis, Structure and Evolution, University of Houston, Houston, Texas, April 8–10, 1968.
Rabinowitz, J., Woeller, F., Flores, J., and Krebsbach, R.: 1969a,Nature 224, 796.
Rabinowitz, J., Flores, J., Krebsbach, R., and Rogers, G.: 1969,Nature 224, 795.
Schwartz, A. and Ponnamperuma, C.: 1968,Nature 218, 442.
Skoda, J. and Moravek, J.: 1966,Tetrahedron Letters, 4167.
Thilo, E. and Grunze, H.: 1955,Z. Anong. Allgem. Chem. 281, 262.
Vegotsky, A.: 1961, Ph.D. Dissertation, Florida State University.
Waehneldt, T. V. and Fox, S. W.: 1967,Biochim. Biophys. Acta 134, 1.
Weiss, S. B., Smith, S. W., and Kennedy, E. P.: 1958,J. Biol. Chem. 231, 53.
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Chang, S., Williams, J.A., Ponnamperuma, C. et al. Phosphorylation of uridine with inorganic phosphates. Space Life Sciences 2, 144–150 (1970). https://doi.org/10.1007/BF01101280
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DOI: https://doi.org/10.1007/BF01101280