Advertisement

Plant Foods for Human Nutrition

, Volume 37, Issue 2, pp 161–168 | Cite as

Effect of wheat bran supplementation on blood sugar, glycosylated protein and serum lipids in NIDDM subjects

  • Indirani Mani
  • Uliyar V Mani
Article

Abstract

Wheat bran supplementation (11 gm per day) was carried out for a period of two months in 30 maturity onset diebetics. The efficacy of bran supplementation was monitored by measuring the fasting and 2 h post prandial blood sugar levels, glycosylated serum protein levels, glycosylated albumin levels and serum lipid and lipoprotein cholesterol levels. The results indicated a transient reduction in fasting and 2 h post prandial blood sugar levels after one month's bran therapy. No appreciable changes in the serum glycosylated protein levels, glycosylated albumin levels, serum lipids and lipoprotein cholesterol levels were observed during the period of supplementation.

Key words

Diabetes mellitus serum lipids glycosylated proteins 

Abbreviations

TC

total cholesterol

HDL-C

high density lipoprotein cholesterol

LDL-C

low density lipoprotein cholesterol

VLDL-C

Very low density lipoprotein cholesterol

TG

triglycerides

PL

phospholipids

FFA

free fatty acids

G-Alb

glycosylated albumin

GSP

glycosylated serum proteins

NIDDM

Non Insulin Dependent Diabetes Melitus

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Savage PJ, Knowler WC (1984) Diet therapy for Type II (Non-Insulin dependent diabetes mellitus) Can new approaches improve therapeutic results? Reviews in Clinical nutrition 54:71–87Google Scholar
  2. 2.
    Story L, Anderson JW, Chen JWL, Karouns D, Jefferson BW (1985) Adherence to high carbohydrate high fibre diets. Long term studies on non-obese diabetic men. The American Diabetic Association 85:1105–1110Google Scholar
  3. 3.
    Munoz JM (1984) Fibre and diabetes. Diabetes Care 7:297–300Google Scholar
  4. 4.
    Bernard RJ, Massey MR, Cherney S, O'Brian LT, Pritein N (1983) Long term use of high complex carbohydrate high fibre low fat diet and exercise in the treatment of NIDDM patients. Diabetes Care 6:268–272Google Scholar
  5. 5.
    Mahalko JR, Sandstead HH, Johnson LK, Inman LF, Milne DB, Warner RC, Haunoz EA (1984) Am J Clin Nutr 39:25–34Google Scholar
  6. 6.
    Truswell AS (1984) Dietary fibre and lipid metabolism In: Vichai Tanphaichitr (ed) Human nutrition, Better nutrition Better life. Winai Dahlan, Veranunt Suphakaran and Aree Valyasevi. Publ. by Aksornsmai Press, Bangkok, Thailand, pp478–488Google Scholar
  7. 7.
    Mani UV, Goswami S, Mani I, Patel S, Gujral S (1985) Effect of wheat bran supplementation on serum lipids in diabetic rats. Arogya J Hlth Sci XI: 186–170Google Scholar
  8. 8.
    Goswamy S, Mani I, Mani UV (1985). Effect of wheat bran supplementation on tissue lipids in diabetic rats. Ind J Biochem Biophys 22:240–243Google Scholar
  9. 9.
    Miller GR, Miller NE (1975). Plasma HDL concentration and development of ischemic heart disease Lancet 1:16–19Google Scholar
  10. 10.
    Gordon T, Cantelli WB, Hjortland MC, Kannal WB and Dawber TR (1977) HDL as a protective factor against CHD. The Framingham Study. Am J Med 62:707–714Google Scholar
  11. 11.
    Gopalan C, Shastri BVR, Balasubramanian SC (1984). Nutritive value of Indian Foods. Published by ICMR, New DelhiGoogle Scholar
  12. 12.
    CSIR Diagnostic kit for blood sugar. Method of Hultman E (1959) Nature (London) 183:108–109Google Scholar
  13. 13.
    Nayak SS, Pattabhiraman TN (1982) Determination of glucosyl albumin by phenol-sulphuric acid reaction in hyperglycemia. Ind J Med Res 76:305–310Google Scholar
  14. 14.
    Mani I, Patel JJ, Mani UV (1986) Measurement of serum glycosylated protein and glycosylated low density lipoprotein levels in the serum of diabetics. Biochem Med Academic Press (in press)Google Scholar
  15. 15.
    Foster LB, Dunn RJ (1973) Stable reagents for determination of serum triglyceride by a colorimetric Hantzsch condensation method. clin Chem 19:338–395Google Scholar
  16. 16.
    Marinetti CV (1962) Chromatographic separation, identification and analysis of phosphatides. J Lip Res 3:1–4Google Scholar
  17. 17.
    Duncombe WG (1962) The colorimetric determination of long chain fatty acids in the 0.05–05 umole range. Biochem. J 83:6–10Google Scholar
  18. 18.
    Warnick GR, Mayfield CBS, Benderson JBS, Chem JS, Albert JJ (1982) HDL-cholesterol quantitation by phosphotungstate—Mg+2 polyethylene glycol precipitation. Both with Enzymic cholesterol assay compared with the Lipid Research method. Am J Clin Pathol 78:718–721Google Scholar
  19. 19.
    CSIR Diagnostic kit for cholesterol Method of Watson D (1960). Clin Chim Acta 5:637–640Google Scholar
  20. 20.
    Wieland H, Seidel D (1983) A simple specific method for precipitation of low density lipoprotein. J Lip Res 24:904–909Google Scholar
  21. 21.
    Viswanathan M, Ramachandran A, Mohan V, Snehlatha C (1981) High Carbohydrate high fibre diet in diabetes mellitus. J Diab Assoc India 21:90–96Google Scholar
  22. 22.
    Ray TK, Munseli KM, Knight LC, Malmud LS, Owen OE, Boden G (1983) Long term effects of dietary fibre on glucose tolerance and gastric emptying in non-insulin dependent diabetic patients. Am J Clin Nutr 37:376–381Google Scholar

Copyright information

© Martinus Nijhoff Publishers 1987

Authors and Affiliations

  • Indirani Mani
    • 1
  • Uliyar V Mani
    • 1
  1. 1.Department of Foods & NutritionMS University of Baroda, BarodaGujaratIndia

Personalised recommendations