Three groups with 12 weanling male albino rats were group fed for 90 days on a standard laboratory rat diet plus 20% coconut oil either without a supplement or with the addition of 10% curry leaf or 10% mustard seeds. Feed was offered at a level of 10% body weight. At the end of the trial, measurements were made on the total serum cholesterol, high density lipoproteins, low density lipoproteins, and very low density lipoproteins fractions, release of lipoproteins into the circulation, lecithin cholesterol acyl transferase activity and lipoprotein lipase activity. Feed intake and mean body weight of the rats on each treatment was not significantly different. Both spices resulted in a reduction in total serum cholesterol and LDL+VLDL, an increase in the HDL, lower release of lipoproteins into the circulation and an increase in the LCAT activity.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Iyer UM, Mani UV (1990) Studies on the effect of curry leaves supplementation on lipid profile, glycated proteins and amino acids in non insulin dependent diabetic patients. Plant Foods Hum Nutr 40: 275–282.
Sharma RD, Raghuram TC (1991) Hypolipidaemic effect of fenugreek seeds: A clinical study. Phyt Ther Res 30: 145–147.
Sharma RD, Raghuram TC, Sudhakar Rao N (1990) Effect of fenugreek seeds on blood glucose and serum lipids in Type I diabetes. Eur J Clin Nutr 44: 301–306.
Abraham A, Kurup PA (1988) Mechanism of hypercholesterolemia produced by biotin deficiency. J Biosci 12: 187.
Sreenivasan MR, Chandrasekhara N (1992) Effect of mangoginger on lipid status in normal and hypertriglyceridemic rats. J Food Sci Tech 29: 130–131.
Sreenivasan MR, Satyanarayana MN (1988) Influence of capsaicin, eugenol, curcumin and ferulic acid on sucrose induced hypertriglyceridemia in rats. Nutr Rep Int 38: 571–579.
Kamanna VS, Chandrasekhara N (1982) Effect of garlic on serum lipoproteins and lipoprotein cholesterol levels in albino rats rendered hypercholesteremic by feeding cholesterol. Lipids 17: 483–488.
Frederickson DS, Levy RI, Leis RS (1976) Fat transport in lipoprotein: An integrated approach to mechanism and disorders. N Engl J Med 276: 32.
Gordon TM, Castelli M, Hjortland M, Kannel WB, Dawber T (1977) High density lipoproteins as a protective factor against coronary heart disease. Am J Med 62: 707.
Miller NE, Relle DS, Forden OH (1977). High density lipoproteins as a protective care control study. Lancet 1977 (i): 965.
Subbarao D, Chandrasekhara N, Satyanarayana MN, Srinivasan M (1970) Effect of curcumin on serum and liver cholesterol levels in cholesterol fed rats. J Nutr 100: 1307.
Sambaiah K, Satyanarayana MN, Rao MVL (1978) Effect of red pepper and capsaicin on fat absorption and liver fat in rats. Nutr Rep Int 18: 521–525.
Gujral S, Bhumra N, Swaroop M (1978) Effect of ginger oleoresin on serum and hepatic cholesterol levels in cholesterol fed rats. Nutr Rep Int 17: 183.
Sambaiah K, Satyanarayana MN (1982) Influence of red pepper and capsaicin on body composition and lipogenesis in rats. J Bio Sci 4: 425.
About this article
Cite this article
Khan, B.A., Abraham, A. & Leelamma, S. Biochemical response in rats to the addition of curry leaf (Murraya koenigii) and mustard seeds (Brassica juncea) to the diet. Plant Food Hum Nutr 49, 295–299 (1996). https://doi.org/10.1007/BF01091978
- Curry leaf
- Lecithin cholesterol acyl transferase