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The biochemistry of learning and memory

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Abstract

An overview of some of the biochemical and molecular events involved in the process of learning and memory are presented in a short review. Two invertebrate models of learning are considered: the gill-withdrawal reflex ofAplysia and avoidance learning inDrosophila melanogaster. Particular attention is paid to the biochemical mechanisms underlying both the development of long-term potentiation (LTP) and passive avoidance learning (PAL) in the young chick. The role of several biological molecules in learning and memory are considered, for example, protein kinase C (PKC), Ca++-Calmodulin kinase II (CaMKII), GAP-43, and glutamate receptors.

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  1. Department of Pharmacology, HSc A133, University of Saskatchewan, S7N OWO, Saskatoon, SK, Canada

    Danielle D. Fagnou & John M. Tuchek

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Fagnou, D.D., Tuchek, J.M. The biochemistry of learning and memory. Mol Cell Biochem 149, 279–286 (1995). https://doi.org/10.1007/BF01076589

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