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Studies of human amebiasis

III. Ameboma: A radiologic manifestation of amebic colitis

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Abstract

Four patients with well-documented amebic colitis had colonic deformities suggestive of ameboma. When barium enema examinations were performed, each of the 4 had cecal “coning,” and 1 had an additional sigmoid lesion. Only 1 patient with a cecal lesion had a palpable, tender mass in the right lower quadrant. After treatment with metronidazole (multiple courses in 1 case), there was clinical and parasitologic cure in each case and radiologic improvement in the 3 who were available for followup. Since ameboma may be confused with carcinoma, a search for amebae in stool and an indirect hemagglutination test for amebiasis may prevent unnecessary and potentially disastrous surgery.

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This work was supported by grants from The John A. Hartford Foundation, Inc, New York, New York; the National Institutes of Health General Research Support Grant RR05420 to the Medical University of South Carolina; the South Carolina State Appropriations for Research; and the Veterans Administration

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Pittman, F.E., Pittman, J.C. & El-Hashimi, W.K. Studies of human amebiasis. Digest Dis Sci 18, 1025–1031 (1973). https://doi.org/10.1007/BF01076516

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