Abstract
The running-wheel activity of young adult, male mice from all three Fuller brain weight lines and their parent stock (Binghamton HETS) was observed over an entire 1-week testing period. When food was removed from cages with available running wheels for a period of 24 h, high-brain weight and HET mice increased their average running, whereas the median- and low-brain weight lines did not. Frequency polygons of total miles traveled during this entire week of testing (range, 1.01 to 43.37 mi) were also examined for each genotype. The implication of these results with respect to the use of these genotypes for exploring relations of brain size to behavior are considered; generally, issues surrounding choice of “controls” when explaining phenotype/genotype relations are discussed.
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This research was supported in part by NSF (DAR7911233).
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Burright, R.G., Engellenner, W.J., Diehl, C.E. et al. Wheel-running activity of Binghamton heterogeneous and fuller brain weight mice. Behav Genet 13, 591–599 (1983). https://doi.org/10.1007/BF01076404
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DOI: https://doi.org/10.1007/BF01076404