Fatigue and recovery contractile properties of young and elderly men

  • C. Klein
  • D. A. Cunningham
  • D. H. Paterson
  • A. W. Taylor


The 24 h recovery pattern of contractile properties of the triceps surae muscle, following a period of muscle fatigue, was compared in physically active young (25 years,n = 10) and elderly (66 years,n = 7) men. The fatigue test protocol consisted of 10 min of intermittent submaximal 20 Hz tetani. The maximal twitch (pt) and tetanic force at 3 frequencies (10, 20 and 50 Hz) were determined at baseline and at 15 min, 1, 4 and 24 h after fatiguing the muscle. Maximal voluntary contraction (MVC) and vertical jump (MVJ) were also assessed. The loss of force during the fatigue test was not significantly different between the young (18±13%) and elderly (22±15%). Both groups showed similar and significant reductions of Pt (15%), tetanic force (10 to 35%) and rate of force development (dp/dt) (20%) 15 min and 1 h into recovery. The loss of force was greater at the lower stimulation frequencies of 10 and 20 Hz. Time-to-peak tension was unchanged from baseline during recovery in either group. The average rate of relaxation of twitch force (−dPt/dt) was decreased (p<0.05) and half-relaxation time significantly increased at 15 min and 1 h in the elderly but not the young. The findings indicate that after fatiguing contractions, elderly muscle demonstrates a slower return to resting levels of the rate and time course of twitch relaxation compared to the young.

Key words

Muscle fatigue Aging Electrical stimulation Voluntary contraction 


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  1. Aniansson A, Grimby G, Hedberg M, Rundgren A, Sperling L (1978) Muscle function in old age. Scan J Rehab Med [Suppl] 6:43–49Google Scholar
  2. Aniansson A, Grimby G, Nygaard E, Saltin B (1980) Muscle fiber composition and muscle fiber area in various age groups. Muscle Nerve 2:271–272Google Scholar
  3. Bellemare F, Woods JJ, Johansson R, Bigland-Ritchie B (1983) Motor-unit discharge rates in maximal voluntary contractions of three human muscles. J Neurophysiol 50:1380–1392Google Scholar
  4. Bigland-Ritchie B, Jones DA, Woods JJ (1979) Excitation frequency and muscle fatigue: electrical responses during human voluntary and stimulated contractions. Exp Neurol 64:414–427Google Scholar
  5. Costill DL, Fink WJ, Pollock ML (1976) Muscle fiber composition and enzyme activities of elite distance runners. Med Sci Sports 8:96–100Google Scholar
  6. Cunningham DA, Rechnitzer PA, Howard JH, Donner AP (1987) Exercise training of men at retirement: clinical trial. J Gerontol 42:17–23Google Scholar
  7. Davies CTM, White MJ (1981) Muscle weakness following eccentric work in man. Pflügers Arch 392:168–171Google Scholar
  8. Davies CTM, White MJ (1982) Muscle weakness following dynamic exercise in humans. J Appl Physiol 53:236–241Google Scholar
  9. Davies CTM, White MJ (1983a) Contractile properties of the elderly human triceps surae. Gerontol 29:19–25Google Scholar
  10. Davies CTM, White MJ (1983b) Effects of dynamic exercise on muscle function in elderly men, aged 70 years. Gerontol 29:26–31Google Scholar
  11. Davies CTM, Young K (1985) Muscle weakness following sustained and rhythmic isometric contractions in man. Eur J Appl Physiol 54:301–305Google Scholar
  12. Davies CTM, Mecrow IK, White MJ (1982) Contractile properties of the human triceps surae with some observations on the effects of temperature and exercise. Eur J Appl Physiol 49:255–269Google Scholar
  13. Dawson MJ, Gadian DG, Wilkie DR (1980) Mechanical relaxation rate and metabolism studied in fatiguing muscle by phosphorus nuclear magnetic resonance. J Physiol 299:465–484Google Scholar
  14. Dixon WJ, Massey FJ (1957) Introduction to statistical analysis, New York, McGraw-HillGoogle Scholar
  15. Edwards RHT, Hill DK, Jones DA (1975) Metabolic changes associated with the slowing of relaxation in fatigued mouse muscle. J Physiol 251:287–301Google Scholar
  16. Edwards RHT, Hill DK, Jones DA, Merton PA (1977) Fatigue of long duration in human skeletal muscle after exercise. J Physiol 272:769–778Google Scholar
  17. Ermini M, Szelenyi I, Moser P, Verzar F (1971) The ageing of skeletal (striated) muscle by changes of recovery metabolism. Gerontologia 17:300–311Google Scholar
  18. Fitts RH, Troup JP, Witzmann FA, Holloszy JO (1984) The effect of ageing and exercise on skeletal muscle function. Mech Ageing Devel 27:161–172Google Scholar
  19. Grabowski W, Lobsiger EA, Luttgau HCH (1972) The effect of repetitive stimulation at low frequencies upon the electrical and mechanical activity of single muscle fibers. Pflügers Arch 334:222–239Google Scholar
  20. Hermansen L (1981) Effect of metabolic changes on force generation in skeletal muscle during maximal exercise. In: Porter R, Whelan J (eds) Human muscle fatigue: physiological mechanisms. Ciba Foundation symposium 82. Pitman Medical, London, pp 75–88Google Scholar
  21. Hultman E, Sjoholm H, Sahlin K, Edstrom L (1981) Glycolytic and oxidative energy metabolism and contraction characteristics of intact human muscle. In: Porter R, Whelan J (eds) Human muscle fatigue: physiological mechanisms. Ciba Foundation Symposium 82. Pitman Medical, London, pp 19–40Google Scholar
  22. Jennekens FGI, Tomlinson BE, Walton JN (1971) Histochemical aspects of five limb muscles in old age. An autopsy study. J Neurol Sci 14:259–276Google Scholar
  23. Jones DA (1981) Muscle fatigue due to changes beyond the neuromuscular junction. In: Porter R, Whelan J (eds) Human muscle fatigue: physiological mechanisms. Ciba Foundation Symposium 82. Pitman Medical, London, pp 178–196Google Scholar
  24. Jones PRM, Pearson J (1969) Anthropometric determination of leg fat and muscle plus bone volumes in young male and female adults. J Physiol 204:63p-66pGoogle Scholar
  25. Larsson L, Karlsson J (1978) Isometric and dynamic endurance as a function of age and skeletal muscle characteristics. Acta Physiol Scand 104:129–136Google Scholar
  26. Larsson L, Sjodin B, Karlsson J (1978) Histochemical and biochemical changes in human skeletal muscle with age in sedentary males, age 22–65 years. Acta Physiol Scand 103:31–39Google Scholar
  27. Lexell J, Henriksson-Larsen K, Winblad B, Sjostrom M (1983) Distribution of different fiber types in human skeletal muscles: effects of aging studied in whole muscle cross sections. Muscle Nerve 6:588–595Google Scholar
  28. Lind AR, Petrofsky JS (1978) Isometric tension from rotary stimulation of fast and slow cat muscles. Muscle Nerve 1:213–218Google Scholar
  29. McDonagh MJN, White MJ, Davies CTM (1984) Different effects of aging on the mechanical properties of human arm and leg muscles. Gerontol 30:49–54Google Scholar
  30. McNamara MC, Miller AT jr, Shen AL, Wood JJ (1978) Restitution of ATP and creatine phosphate after experimental depletion in young, adult, and old rats. Gerontol 24:95–103Google Scholar
  31. Moritani T, Muro M, Kijima A (1985) Electromechanical changes during electrically induced and maximal voluntary contractions: Electrophysiologic responses of different muscle fiber types during stimulated contractions. Exper Neurol 88:471–483Google Scholar
  32. Newton JP, Yemm R (1986) Changes in the contractile properties of the human first dorsal interosseous muscle with age. Gerontol 32:98–104Google Scholar
  33. Patrick JM, Bassey EJ, Fentem PH (1983) The rising ventilatory cost of bicycle exercise in the seventh decade: a longitudinal study of nine healthy men. Clin Sci 65:521–526Google Scholar
  34. Richardson D, Shewchuk R (1980) Comparison of calf muscle blood flow responses to rhythmic exercise between mean age 25- and 74-year-old men. Proc Soc Exper Biol 164:550–555Google Scholar
  35. Taylor DJ, Crowe M, Bore PJ, Styles P, Arnold DL, Radda GK (1984) Examination of the energetics of aging skeletal muscle using nuclear magnetic resonance. Gerontol 30:2–7Google Scholar
  36. Vandervoort AA, McComas AJ (1986) Contractile changes in opposing muscles of the human ankle joint with aging. J Appl Physiol 61:361–367Google Scholar
  37. Winer BJ (1971) Statistical principles in experimental design, 2nd ed, New York, McGraw-Hill, p 796Google Scholar

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • C. Klein
    • 1
  • D. A. Cunningham
    • 1
    • 2
  • D. H. Paterson
    • 1
  • A. W. Taylor
    • 1
    • 2
  1. 1.Faculty of Physical EducationThe University of Western OntarioLondonCanada
  2. 2.Department of Physiology, Medical Sciences BuildingUniversity of Western OntarioLondonCanada

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