Skip to main content
SpringerLink
Log in

Noninfectious ascitic fluid leukocytosis associated with penetrating duodenal ulcer

  • Case Report
  • Published:
The American Journal of Digestive Diseases Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Summary

Ascitic fluid leukocytosis occurring in the cirrhotic patient in the absence of positive peritoneal cultures is often difficult to explain. A unique case of a patient with alcoholic cirrhosis, sterile ascites, and ascitic fluid leukocytosis demonstrated prior to the perforation of a duodenal ulcer has been presented. Based on the patient's clinical course and the pathological events in peptic ulceration of the stomach and duodenum, it is possible to postulate an explanation for the sterile ascitic fluid leukocytosis observed in this patient.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Conn HO, Fessel JM: Spontaneous bacterial peritonitis in cirrhosis: Variations on a theme. Medicine 50:161–197, 1971

    PubMed  Google Scholar 

  2. Curry N, McCallum RW, Guth PH: Spontaneous peritonitis in cirrhotic ascites. A decade of experience. Am J Dig Dis 19:685–692, 1974

    PubMed  Google Scholar 

  3. Kline MM, McCallum RW, Guth PH: The clinical value of ascitic fluid culture and leukocyte count studies in alcoholic liver disease. Gastroenterology 70:408–412, 1976

    PubMed  Google Scholar 

  4. Paddock FK: The diagnostic significance of serous fluids in disease. N Engl J Med 223:1010–1015, 1940

    Google Scholar 

  5. Burack WR, Hollister RM: Tuberculous peritonitis. A study of forty-seven proven cases encountered by a general medical unit in twenty-five years. Am J Med 28:510–523, 1960

    PubMed  Google Scholar 

  6. Conn HO: Spontaneous bacterial peritonitis: Multiple revisitations. Gastroenterology 70:455–457, 1976

    PubMed  Google Scholar 

  7. Bar-Meir S, Conn HO: Analysis of ascitic fluid in cirrhosis: The “normal” number of leukocytes. Gastroenterology 69:807, 1975 (abstract)

    Google Scholar 

  8. Morson BC, Dawson IMP: Gastrointestinal Pathology. Oxford, Blackwell Scientific Publications, 1972, pp 110–127

    Google Scholar 

  9. Karsner HT: The pathology of peptic ulcer of the stomach, JAMA 35:1376–1380, 1925

    Google Scholar 

  10. Crohn BB, Weiskopf S, Aschner PW: The life cycle of peptic ulcer. Arch Intern Med 35:405–422, 1925

    Google Scholar 

  11. Haubrick WS, Roth JLA, Bockus HL: The clinical significance of penetration and confined perforation in peptic ulcer disease. Gastroenterology 25:173–201, 1953

    PubMed  Google Scholar 

  12. Haubrick WS: The clinical recognition and pathological anatomy of intractability in peptic ulcer disease. Ann NY Acad Sci 99:114–120, 1962

    PubMed  Google Scholar 

  13. Swisher WP, Baker LA, Bennett HD: Peptic ulcer in Laennec's cirrhosis. Am J Dig Dis 22:291–294, 1955

    PubMed  Google Scholar 

  14. Orloff MJ, Chandler JG, Alderman SJ, Keiter JE, Rosen H: Gastric secretion and peptic ulcer following portacaval shunt in man. Ann Surg 170:515–527, 1969

    PubMed  Google Scholar 

  15. Bonnevie, O: Causes of death in duodenal and gastric ulcer. Gastroenterology 73:1000–1004, 1977

    PubMed  Google Scholar 

  16. Stanley MM, McKeever JW, Bedford DE: Ascitic fluid (AF) cell counts in “uncomplicated” cirrhotics: Evidence that cell concentrations increase during diuresis. Gastroenterology 66:782, 1974

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Medicine, University of Florida, College of Medicine, 32610, Gainesville, Florida

    Richard F. Harty MD & William M. Steinberg MD

Authors
  1. Richard F. Harty MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. William M. Steinberg MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Harty, R.F., Steinberg, W.M. Noninfectious ascitic fluid leukocytosis associated with penetrating duodenal ulcer. Digest Dis Sci 23, 1132–1136 (1978). https://doi.org/10.1007/BF01072891

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01072891

Keywords

Search

Navigation