Skip to main content
Log in

Gastrointestinal tract metastasis in patients with germ-cell tumor of the testis

  • Original Articles
  • Published:
The American Journal of Digestive Diseases Aims and scope Submit manuscript


A study of the incidence and clinical course of testicular germ-cell tumor metastatic to the gastrointestinal tract is presented. Gastrointestinal tract metastasis occurred in 25 cases, 5% of all patients evaluated with germ-cell tumor of the testis. Although embryonal carcinoma was the dominant component in all cases, elements of choriocarcinoma were found in 20 cases and HCG was positive in 22 cases. Metastasis occurred most commonly by direct invasion from adjacent tumor. The most frequent site of gastrointestinal involvement was the proximal small intestine. Involvement of the duodenum was noted in seven cases. The most common gastrointestinal tract manifestations were intestinal obstruction and gastrointestinal bleeding. Although a variety of therapeutic modalities were tried, the average length of survival from the time of diagnosis of gastrointestinal metastasis to death was six months.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others


  1. Borskii AA: Diagnosis, staging and natural history of testicular tumors. Cancer 32:1202–1205, 1973

    Google Scholar 

  2. Wittes RE, Yagoda A, Silvay O, Magill GB, Whitmore, Krakoff IH, Golbey RB: Chemotherapy of germ cell tumors. Cancer 37:637–645, 1976

    Google Scholar 

  3. Chiappa S, Uslenghi C, Galli G, Ravasi G, Bonadonna G: Lymphangiography and endolymphatic radiotherapy in testicular tumors. Br J Radiol 39:498–512, 1966

    Google Scholar 

  4. Mostofi RK: Testicular tumors. Cancer 32:1186–1201, 1973

    Google Scholar 

  5. Dixon FJ, Moore RA: Testicular tumors: A clinicopathologic study. Cancer, 6:427–454, 1953

    Google Scholar 

  6. Hajdu SI, Hajdu EO: Cytopathology of Sarcomas and Other Nonepithelial Malignant Tumors. Philadelphia, W. B. Saunders, 1976, pp 141–182

    Google Scholar 

  7. Willis RA: The Spread of Tumours in the Human Body, 2nd ed. London, Butterworth, 1952.

    Google Scholar 

  8. Ray B, Hajdu SI, Whitmore WF: Distribution of retroperitoneal lymph node metastases in testicular germ cell tumors. Cancer 33:340–348, 1974

    Google Scholar 

  9. MacDonald EJ: Multiple Primaries in Cancer of the Gastrointestinal Tract, The University of Texas M. D. Anderson Hospital and Tumor Institute, Chicago, Year Book Medical Publishers, 1967, pp 296–282.

    Google Scholar 

  10. Veen HF, Oscarson JEA, Malt RA: Alien cancers of the duodenum. Surg Gynecol Obstet 143:39–42, 1976

    Google Scholar 

  11. Ngan H: Involvement of the duodenum by metastases from tumors of the genital tract. Br J Radiol 43:701–705, 1970

    Google Scholar 

  12. Ehrlich AM, Stalder G, Geller W, Sherlock P: Gastrointestinal manifestations of malignant lymphoma. Gastroenterology 54:1115–1121, 1968

    Google Scholar 

  13. Meyers MA, McSweeney J: Secondary neoplasms of the bowel. Radiology 105:1–11, 1072

    Google Scholar 

  14. Staubitz WJ, Magoss IV, Grace JT, Schenk WG: Surgical management of testis tumors. J Urol 101:350–355, 1969

    Google Scholar 

Download references

Author information

Authors and Affiliations


Additional information

Supported in part by the American Cancer Society Clinical Fellowship 3697 to Dr. Chait, and American Cancer Society Junior Faculty Clinical Fellowship 352 to Dr. Kurtz.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chait, M.M., Kurtz, R.C. & Hajdu, S.I. Gastrointestinal tract metastasis in patients with germ-cell tumor of the testis. Digest Dis Sci 23, 925–928 (1978).

Download citation

  • Issue Date:

  • DOI: