Abstract
Lifelong records of schizophrenic illnesses were examined in order to compare the occurrence and characteristics of depressive syndrome in the pre-phenothiazine era and with neuroleptic treatments. It was found that a depressive syndrome similar to endogenous depressive psychosis develops spontaneously and independently of neuroleptic medication. The relationship of this endogenous syndrome to the postpsychotic depression of other origin is discussed.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Ayd F: Drug-induced depression—fact or fallacy.NY State J Med 58:354–56, 1958.
McGlashan TH, Carpenter WT: Postpsychotic depression in schizophrenia.Arch Gen Psychiatry 33:231–39, 1976.
Planansky K, Johnston R: Depressive syndrome in schizophrenia.Acta psychiat scand 57:207–218, 1978.
Strömgren E: Psychoses caused by neuroleptics.Encephale 53, Suppl: 170–174, 1964.
Bohaček N: Depression-inducing potential of neuroleptics. In M Lader and R Garcia (eds):Aspects of Depression. Madrid, World Psychiatric Association Congress, 1973, pp. 225–231.
Helmchen H, Hippius H: Depressive syndrome im Verlauf neuroleptischer Therapie.Nervenarzt 38:455–58, 1967.
Semrad EV, Zaslow SZ: Assisting psychotic patients to recompensate.Mental Hospitals 15:361–66, 1964.
Roth S: The seemingly ubiquitous depression following acute schizophrenic episodes.Am J Psychiatry 127:51–58, 1970.
Kielholz P: Diagnosis and therapy of the depressive states. Documenta Geigi.Acta Psychosomatica I:1–64, 1959.
Heinrich K: Zur Bedeutung des postremissiven Erschöpfungssyndroms für die Rehabilitation Schizophrener.Nervenarzt 38:487–91, 1967.
Huber G: Verlaufsgestalt psychiatrischer Krankheitsbilder und Pharmakotherapie.Med Welt 25:1517–29, 1967.
Kraepelin E: Dementia praecox and paraphrenia. R Mary Barclay (trans),Facsimile, 1919 edition. Huntington, NY, Robert E. Krieger, 1971.
Bleuler E: Dementia praecox or the group of schizophrenias. New York,International Universities Press, 1952.
Donlon PT, Blacker KH: Stages of schizophrenic disorganization and reintegration.J Nerv Ment Dis 157:200–209, 1973.
Planansky K, Johnston R: Preoccupation with death in schizophrenic men.Dis Nerv Syst 38:194–97, 1977.
Battegay R, Gehring A: Vergleichende Untersuchungen an Schizophrenen der präneuroleptischen und der postneuroleptischen Ära.Pharmakopsychiatrie-Neuro-Psychopharmakologie 1:107–122, 1968.
McGlashan TH, Carpenter WT: An investigation of the postpsychotic depressive syndrome.Am J Psychiatry 133:14–19, 1976.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Planansky, K., Johnston, R. Psychotropic drugs and depressive syndrome in schizophrenia. Psych Quart 52, 214–221 (1980). https://doi.org/10.1007/BF01071738
Issue Date:
DOI: https://doi.org/10.1007/BF01071738