Abstract
There is substantial relation between individuals' serum uric acid level and their heights and weights. Even when the association of uric acid level with height/weight is partialed out, significant resemblances in uric acid level are found between biologically related persons (parents and offspring; siblings) but not between spouses. When the association of height/weight is partialed out, uric acid level does not have a significant association with measures of cognitive ability or with educational or occupational attainment.
References
Ashton, G. C., Rashad, M. N., Mi, M. P., Johnson, R. C., Vandenberg, S. G., McClearn, G. E., DeFries, J. C., and Wilson, J. R. (1975). Genetics of blood biochemistry. Paper presented to Pacific Slope Biochemical Conference, Honolulu, June.
Boyle J. A., Grieg, W. R., Jasani, M. K., Duncan, A., Diver, M., and Buchanan, W. W. (1967). Relative roles of genetic and environmental factors in the control of serum uric acid levels in normouricaemic subjects.Ann. Rheum. Dis. 26:234–238.
DeFries, J. C., Vandenberg, S. G., McClearn, G. E. Kuse A. R., Wilson, J. R., Ashton, G. C., and Johnson, R. C. (1974). Near identity of cognitive structure in two ethnic groups.Science 183:338–339.
DeFries, J. C., Ashton, G. C., Johnson, R. C., Kuse, A. R. McClearn, G. E., Mi, M. P., Rashad, M. N., Vandenberg, S. G., and Wilson, J. R. (1976). Parent-offspring resemblance for specific cognitive abilities in two ethnic groups.Nature 261:131–133.
DeFries, J. C., Johnson, R. C., Kuse, A. R., McClearn, G. E., Polovina, J., Vandenberg, S. G., and Wilson, J. R. (1979). Familial resemblances for specific cognitive abilities.Behav. Genet. 9:23–43.
French, J. G., Dodge, H. J., Kjelsberg, M. O., Mikkelsen, W. M., and Shull, W. J. (1967). A study of familial aggregation of serum uric acid levels in the population of Tecumseh, Michigan, 1959–1960.Am. J. Epidemiol. 86:214–224.
Gulbrandsen, C. L., Morton, N. E., Rao, D. C., Rhoads, G. G., and Kagan, A. (1979). Determinants of plasma uric acid.Hum. Genet. 50:307–312.
Johnson, R. C., DeFries, J. C., Wilson, J. R., McClearn, G. E., Vandenberg, S. G., Ashton, G. C., Mi, M. P., and Rashad, M. N. (1976). Assortative marriage for specific cognitive abilities in two ethnic groups.Hum. Biol. 48:343–352.
Kaiser, H. F. (1960). The application of electronic computers to factor analysis.Educ. Psychol. Meas. 20:141–151.
Kasl, S. V. (1974). Are there any promising biochemical correlates of achievement behavior and motivations? The evidence for serum uric acid and serum cholesterol.Rev. Educ. Res. 44:447–462.
Kuse, A. R. (1977). Familial resemblances for cognitive abilities estimated from two test batteries in Hawaii. Unpublished doctoral dissertation, University of Colorado, Boulder.
Mueller, E. F., Kasl, S. V., Brooks, G. W., and Cobb, S. (1970). Psychosocial correlates of serum uric acid level.Psychol. Bull. 73:238–257.
O'Brien, W. M., Burch, t. A., and Bunim, J. J. (1966). Genetics of hyperuricemia in Blackfeet and Pima Indians.Ann. Rheum. Dis. 25:117–119.
Osborne, R. H., and Degeorge, F. V. (1959).Genetic Basis of Morphological Variation. Harvard University Press, Cambridge, Mass.
Reiss, A. J., Duncan, O. D., Hatt, P. K., and North, C. C. (1961).Occupations and Social Class, Free Press, Glencoe, Ill.
Wilson, J. R., DeFries, J. C., McClearn, G. E., Vandenberg, S. G., Johnson, R. C., Mi, M. P., and Rashad M. N. (1975). Cognitive abilities: Use of family data as a control to assess sex and age differences in two ethnic groups.Int. J. Aging Hum. Dev. 6:261–276.
Author information
Authors and Affiliations
Additional information
The results reported here are made possible by a collaboration of a group of investigators (G. C. Ashton, R. C. Johnson, M. P. Mi, and M. N. Rashad at the University of Hawaii and J. C. DeFries, G. E. McClearn, S. G. Vandenberg, and J. R. Wilson at the University of Colorado) supported by NSF Grant GB-34720 and Grant HD-06669 from the National Institute of Child Health and Human Development.
Rights and permissions
About this article
Cite this article
Ahern, F.M., Johnson, R.C. & Ashton, G.C. Family resemblances in serum uric acid level. Behav Genet 10, 303–307 (1980). https://doi.org/10.1007/BF01067775
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01067775