Behavior Genetics

, Volume 2, Issue 1, pp 3–19 | Cite as

The investigation of linkage between a quantitative trait and a marker locus

  • J. K. Haseman
  • R. C. Elston


Procedures are given, using sib pairs, for estimating linkage between a knownm-allele locus and a hypothesized two-allele locus that governs a quantitative trait. Random mating and linkage equilibrium are assumed. Also given are parametric and nonparametric methods for detecting linkage when the trait in question is governed by several two-allele loci, provided there is no epistasis.


Quantitative Trait Random Mating Marker Locus Nonparametric Method Linkage Equilibrium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Publishing Corporation 1972

Authors and Affiliations

  • J. K. Haseman
    • 1
  • R. C. Elston
    • 2
  1. 1.National Institute of Environmental Health SciencesResearch Triangle Park
  2. 2.Department of Biostatistics and the Genetics CurriculumUniversity of North CarolinaChapel Hill

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