Abstract
The activity of mice from two selected lines, differing in degree of paw preference, was observed. Differences in the relative frequencies of certain categories of activity were found both between the two lines of mice and betwen the sexes; sex differences were in general more pronounced between mice from the strongly lateralized line. This finding is consistent with a theory which attempts to relate lateralization of function in the nervous system to developmental effects of differences in metabolism of gonadal steroids.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Arnold, A. P., and Gorski, R. A. (1984). Gonadal steroid induction of structural sex differences in the central nervous system.Annu. Rev. Neurosci. 7:413–442.
Bailey, W. H., Collins, R. L., and Lahita, R. G. (1985). Cerebral lateralization: Association with serum antibodies to DNA in selectively bred mouse lines. Society for Neuroscience, 15th Annual Meeting, Dallas, Tex.
Collins, R. L. (1981). A demonstration of an inheritance of the direction of asymmetry that is consistent with the notion that genetic alleles are left-right indifferent.Behav. Genet. 11:596 (abstr.).
Collins, R. L. (1985). On the inheritance of the direction and degree of asymmetry. In Glick, S. D. (ed.)Cerebral Lateralization in Subhuman Species, Academic Press, New York, pp. 41–70.
Collins, R. L., Carlson, G. A., and Nadeau, J. H. (1985). Differential distribution ofH-2 haplotypes in lines of mice selectively bred for degree of lateralization. Society for Neuroscience, 15th Annual Meeting, Dallas, Tex.
Geschwind, N., and Behan, P. (1982). Left-handedness: Association with immune disease, migraine, and developmental learning disorder.Proc. Natl. Acad. Sci. 79:5097–5100.
Kolb, B., Sutherland, P. J., Nonneman, A. J., and Wishaw, I. Q. (1982). Asymmetry in the cerebral hemispheres of the rat, mouse, rabbit and cat: The right hemisphere is larger.Exp. Neurol. 78:348–359.
Sokal, R. R., and Rohlf, F. J. (1981).Biometry, 2nd ed. W. H. Freeman, San Francisco.
Ward, R., and Collins, R. L. (1985). Brain size and shape in strongly and weakly lateralized mice.Brain Res. 328:243–249.
Author information
Authors and Affiliations
Additional information
This work was supported in part by Grant A9959 from the Natural Sciences and Engineering Research Council of Canada and in part by the Fonds Institutionnel de Recherche de l'Université du Québec. We thank Robert L. Collins, of the Jackson Laboratory, for providing mice from his two selected lines.
Rights and permissions
About this article
Cite this article
Ward, R., Giguère, L. & Yves, M.S. Some behavioral differences between strongly and weakly lateralized mice. Behav Genet 16, 575–584 (1986). https://doi.org/10.1007/BF01066343
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01066343