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Chromosomal determinants of intermale aggressive behavior in inbred mice

Abstract

A behavioral genetic system has been investigated in which the Y chromosome of DBA/1/Bg mice makes an incremental contribution to the adult aggression of B10D1F t , hybrid mice. Crosses with C57BL/10/Bg, C57BL/6/Bg, and DBA/2/Bg have identified a minimum of one incremental and one decremental (suppressor) genetic factor (in addition to the Y chromosome) which are autosomal and which affect the expression of adult intermale aggression in these strains.

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This study was supported in part by Grants RR 00602-03 from the National Institutes of health, by Grant MH 17088-01 from the National Institute of Mental Health, and by a grant from the Grant Foundation, Inc., awarded to B. E. G. and an NDEA Predoctoral Fellowship awarded to M. K. S.

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Selmanoff, M.K., Maxson, S.C. & Ginsburg, B.E. Chromosomal determinants of intermale aggressive behavior in inbred mice. Behav Genet 6, 53–69 (1976). https://doi.org/10.1007/BF01065678

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Key Words

  • aggression
  • chromosomal determinants
  • hybrids
  • inbred mice