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Effect of the vermian cortex of the anterior lobe of the cerebellum on the background electrical activity of fastigial neurons

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Abstract

The effect of electrical stimulation of the vermian cortex of the anterior lobe of the cerebellum on the activity of neurons of different portions of the fastigial nucleus was studied in acute experiments on cats under light nembutal anesthesia. Inhibitory influences of the cortex (80.6% of the reacting neurons) were manifested in total blocking or decrease in the frequency of the background activity of the neurons and were characterized by a long aftereffect and "rebound." Stimulation of the cortex also had a blocking effect on the inhibitory interaction of adjacent nuclear elements. Facilitatory influences (14.5% of the neurons) were expressed either by an increase of spontaneous discharges of the neurons or by the appearance of activity in rhythm with the stimulation. The effectiveness of cortical stimulation depended on the localization of the stimulating electrodes. Zones of maximum density of projections to a given neuron of the nucleus and convergence and divergence of influences were found in the cerebellar cortex.

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Literature cited

  1. A. S. Amatuni and E. A. Oganesyan, "Effect of the anterior lobe of the cerebellum on neurons of the interpositus nucleus," in: First Orbeli Lectures [in Russian], Izd. AN ArmSSSR, Erevan (1967), pp. 71–73.

    Google Scholar 

  2. V. V. Fanardzhyan and K. A. Astabatyan, "Effect of stimulation of the cerebellar cortex on electrical activity of the dentate nucleus," in: Electrophysiology of the Central Nervous System, Proceedings of the V All-Union Conference of Electrophysiology [in Russian], Tbilisi (1966), pp. 303–304.

  3. A. Ardiuni and O. Pompeiano, "Microelectrode analysis of units of the rostral portion of the nucleus fastigii," Arch. Ital. Biol.,95, 56–70 (1957).

    Google Scholar 

  4. W. W. Chambers and J. M. Sprague, "Functional localization in the cerebellum. I. Organization in longitudinal corticonuclear zones and their contribution to the control of posture, both extrapyramidal and pyramidal," J. Comp. Neurol.,103, 105–129 (1955).

    Google Scholar 

  5. W. W. Chambers and J. M. Sprague, "Functional localization in the cerebellum. II. Somatotopic organization in the cortex and nuclei," Arch. Neurol. Psychiat.,74, 653–680 (1955).

    Google Scholar 

  6. R. S. Dow and G. Moruzzi, The Physiology and Pathology of the Cerebellum, Minneapolis (1958).

  7. R. P. Eager, "Efferent cortico-nuclear pathways in the cerebellum of the cat," J. Comp. Neurol.,120, 81–103 (1963).

    Google Scholar 

  8. J. C. Eccles, M. Ito, and Y. Szentagothai, The Cerebellum as a Neuronal Machine, Springer-Verlag, Berlin-Heidelberg-New York (1967).

    Google Scholar 

  9. M. Ito, N. Kawai, and M. Udo, "The origin of cerebellar induced inhibition and facilitation in the neurons of Deiters and intracerebellar nuclei," Abst. XXIII Intern. Congr. Physiol. Sci., Tokyo, Abstr. 997 (1965), p. 421.

  10. M. Ito, "Integration at the cerebellar subcortical neurons," Proceedings of the International Union of Physiological Sciences, Vol. 7, Washington (1968), p. 217.

  11. A. Jakob, Cited after J. Eccles, M. Ito, and Y. Szentagothai.

  12. J. Jansen and A. Brodal, "Experimental studies on the intrinsic fibers of the cerebellum. II. The cortico-nuclear projection," J. Comp. Neurol.,73, 267–321 (1940).

    Google Scholar 

  13. J. Jansen and A. Brodal, Aspects of Cerebellar Anatomy, Oslo (1954).

  14. L. Maffi and O. Pompeiano, "Cerebellar control of flexor motoneurons. An analysis of postural responses to stimulation of the paramedian lobule in the decerebrate cat," Arch. Ital. Biol.,4, 476–480 (1962).

    Google Scholar 

  15. G. Moruzzi and O. Pompeiano, "Effects of vermian stimulation after fastigial lesions," Arch. Ital. Biol.,95, 31–55 (1957).

    Google Scholar 

  16. R. S. Snider, W. S. McCullock, and H. W. Magoun, "A cerebello-bullbo-reticular pathway for suppression," J. Neurophysiol.,12, 325–334 (1949).

    Google Scholar 

  17. J. M. Sprague and W. Chambers, "Control of posture by reticular formation and cerebellum in the intact anaesthetized and unanaesthetized and in decerebrate cat," Amer. J. Physiol.,176, 52–64 (1954).

    Google Scholar 

  18. I. Woogd, "The cerebellum of the cat," in: Structure and Fibre Connexion, Van Gorcum, Philadelphia (1964).

    Google Scholar 

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Authors
  1. A. S. Amatuni
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  2. É. A. Oganesyan
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Additional information

L. A. Orbeli Institute of Physiology, Academy of Sciences of the Armenian SSR, Erevan. Translated from Neirofiziolgiya, Vol. 2, No. 3, pp. 260–268, May–June, 1970.

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Amatuni, A.S., Oganesyan, É.A. Effect of the vermian cortex of the anterior lobe of the cerebellum on the background electrical activity of fastigial neurons. Neurophysiology 2, 196–202 (1970). https://doi.org/10.1007/BF01063360

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  • DOI: https://doi.org/10.1007/BF01063360

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