Journal of Thrombosis and Thrombolysis

, Volume 2, Issue 1, pp 21–28 | Cite as

Antithrombotic therapy during percutaneous coronary intervention

  • Robert A. Harrington
Frontiers in Thrombocardiology


Ischemic complications of percutaneous coronary intervention occur commonly and are among the major limitations of the procedure. Both platelets and thrombin play an essential role in the response to the arterial injury that follows coronary intervention and in the pathophysiology of the ischemic complications of the procedure. Aspirin and heparin are essential treatments for the patient undergoing coronary intervention. Novel thrombin and platelet inhibitors are being developed that may be useful for improving both acute and long-term clinical outcomes of percutaneous coronary intervention.

Key words

anticoagulants antiplatelets percutaneous transluminal coronary angioplasty 


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Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • Robert A. Harrington
    • 1
  1. 1.Division of CardiologyDuke University Medical CenterDurham

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