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The effect of exercise associated with subchronic poisoning with potassium nitrate and sodium nitrite on the processes of intestinal absorption of D-Xylose in rats

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Abstract

The intestinal absorption of D-xylose was studied during the subchronic poisoning of male Wistar rats with orally administered potassium nitrate and sodium nitrite associated with exercise; running on a moving track during the last two weeks of poisoning. The metabolic parameters of Na+/K+-ATPase, alkaline phosphatase, oxygen uptake, and lactic acid level in the small intestine mucosa were determined one hour after D-xylose treatment. Exercise increased the toxicity of potassium nitrate and sodium nitrite. The experiment demonstrated post-exercise reduction of Dxylose absorption and decrease activity of Na+/K+ -ATPase and alkaline phosphatase. Exercise caused transient hypoxia of the small intestine, which was observed only in the groups subjected to exercise on the day of the determinations.

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Authors and Affiliations

  1. Department of Food Studies and Nutrition Physiology, Military Institute of Hygiene and Epidemiology, Kozielska Str 4, 01-163, Warsaw, Poland

    Ireneusz Grudzinski & Antoni Szymański

  2. Department of Radiobiology, Military Institute of Hygiene and Epidemiology, Kozielska Str 4, 01-163, Warsaw, Poland

    Antoni Szymański & Krzysztof Chomiczewski

Authors
  1. Ireneusz Grudzinski
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  2. Antoni Szymański
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  3. Krzysztof Chomiczewski
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Grudzinski, I., Szymański, A. & Chomiczewski, K. The effect of exercise associated with subchronic poisoning with potassium nitrate and sodium nitrite on the processes of intestinal absorption of D-Xylose in rats. Arch. Environ. Contam. Toxicol. 21, 462–467 (1991). https://doi.org/10.1007/BF01060371

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  • DOI: https://doi.org/10.1007/BF01060371

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