Abstract
There was appreciable uptake of radio-carbon byPanagrellus redivivus, a free-living soil nematode, andBursaphelenchus xylophilus, a plant parasitic nematode, when exposed to a solution of diazinon14C. Both nematode species metabolized diazinon withP. redivivus being more active. Metabolites fromB. xylophilus included0,0-diethyl0-(2-isopropyl-4-methyl-6-pyrimidinyl) phosphate or diazoxon and 2-isopropyl-4-methyl-6-hydroxy-pyrimidine or pyrimidinol. Radioactivity accumulated to a greater extent inB. xylophilus than inP. redivivus. Elimination of radiocarbon was more rapid withP. redivivus than withB. xylophilus, and this resulted in the presence of high levels of the polar pyrimidinol metabolite in the incubation medium ofP. redivivus.
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References
Ahmad, S., and A. J. Forgash: Metabolism of14C-diazinon by gypsy moth larvae. J. Econ. Entomol.68, 571 (1975).
Hechler, H. C.: Reproduction, chromosome, number, and postembryonic development ofPanagrellus redivivus (Nematoda: Cephalobidae). J. Nematol.2, 355 (1970).
Knowles, C. O., and J. E. Casida: Mode of action of organophosphate anthelminthies. Cholinesterase inhibition inAscaris lumbricoides. J. Agr. Food Chem.14, 566 (1966).
Le Patourel, G. N. J., and D. J. Wright: Uptake and metabolism of phorate by the free-living nematodePanagrellus redivivus. Pestic. Biochem. Physiol.4, 135 (1974a).
—: Studies on the mechanisms of accumulation of phorate by the free-living nematodePanagrellus redivivus. Pestic. Biochem. Physiol.4, 144 (1974b).
—: Some factors affecting the susceptibility of two nematode species to phorate. Pestic. Biochem. Physiol.6, 296 (1976).
Levine, N. D., S. Kantor, and G. D. Taylor: Nematocidal activity of some organic phosphorous compounds against horse strongyle larvaein vitro. Am. J. Vet. Res.19, 299 (1958).
Mamiya, Y.: The life history of the pine wood nematode,Bursaphelenchus lignicolus. Jap. J. Nematol.5, 16 (1975).
Mamiya, Y., and T. Kiyohara: Description ofBursaphelenchus lignicolus n. sp. (Nematoda:Aphelenchoididae) from pine wood and histopathology nematode-infested trees. Nematologica.18, 120 (1972).
Mücke, W., K. O. Alt, and H. O. Esser: Degradation of14Clabeled diazinon in the rat. J. Agr. Food Chem.18, 208 (1970).
O'Brien, R. D.: Toxic phosphorus esters. New York: Academic Press (1960).
Smith, B. R., W. C. Dauterman, and E. Hodgson: Selective inhibition of the metabolism of diazinon and diazoxonin vitro by piperonyl butoxide, NIA 16824 and 1-(2-isopropylphenyl) imidazole. Pestic. Biochem. Physiol.4, 337 (1974).
Yang, R. S. H., W. C. Dauterman, and E. Hodgson: Enzymatic degradation of diazinon by rat liver microsomes. Life Sciences8, 667 (1969).
Yang, R. S. H., E. Hodgson, and W. C. Dauterman: Metabolismin vitro of diazinon and diazoxon in rat liver. J. Agr. Food Chem.19, 10 (1971a).
—: Metabolismin vitro of diazinon and diazoxon in susceptible and resistant house flies. J. Agr. Food Chem.19, 14 (1971b).
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Al-Attar, H.J., Knowles, C.O. Diazinon uptake, metabolism, and elimination by nematodes. Arch. Environ. Contam. Toxicol. 11, 669–673 (1982). https://doi.org/10.1007/BF01059153
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DOI: https://doi.org/10.1007/BF01059153