Synopsis
The dry mass of single islet cells was determined in obese-hyperglycemic mice. In one group of animals intense degranulation of the islet cells was brought about by adding glucose to the drinking water and by injections of anti-insulin serum. When the B-cell dry mass of these animals, (1.56±0.05)10−10 g, was compared with that of corresponding cells from starved animals (1.83±0.04)10−10 g, the latter value was found to be significantly higher. The observed difference (about 15%) agrees with that given in previous reports on the percentage of insulin in lyophilised B-cells.
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Petersson, B. The dry mass of the pancreatic B-cells in relation to their content of secretion granules. Histochem J 1, 55–58 (1968). https://doi.org/10.1007/BF01054293
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DOI: https://doi.org/10.1007/BF01054293