Abstract
A new type of bis(crown ether)s containing 15-crown-5 and monoaza-18-crown-6 actively transported Na+ and K+ in opposite directions across a dichloromethane membrane by pH control. The effect of the structure of the ion carriers on their transport abilities was examined. A key point for the molecular design of the carriers is how to give them complexing ability toward Na+ under acidic conditions. A proper choice of the transport conditions was found to be essential for the success of the double uphill transport.
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This paper is dedicated to the memory of the late Dr C. J. Pedersen.
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Okahara, M., Nakatsuji, Y., Sakamoto, M. et al. Bis(crown ether)s as Na+-K+ ATPase model in a liquid membrane. J Incl Phenom Macrocycl Chem 12, 199–211 (1992). https://doi.org/10.1007/BF01053862
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DOI: https://doi.org/10.1007/BF01053862