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Pattern of response in neurosecretory cells of the rat hypothalamic supraoptic nucleus to subiculum stimulation under water deprivation

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Abstract

The effects of water deprivation were investigated in the pattern of response produced by subiculum stimulation in antidromically identified hypothalamic supraoptic neurosecretory cells of lactating rats. In dehydrated animals as compared with the controls, the percentage of neurons responding to subiculum stimulation with an inhibitory action (blockade of antidromic action potential) remained unchanged, although the proportion of differing inhibitory response did alter: numbers of cells with gradually developing inhibitory response increased significantly and fewer cells showed transitory development of inhibition. Inhibitory response emerging as depression of background spike activity showed a quantitative increase, moreover. Plasticity was found to be one distinguishing feature of afferent input from the subiculum to supraoptic nucleus neurosecretory cells and, in particular, a capacity for reorganization under water deprivation.

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Authors
  1. E. A. Lutsik
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A. A. Ukhtomskii Institute of Physiology, State University, Leningrad. Translated from Neirofiziologiya, Vol. 22, No. 2, pp. 243–249, March–April, 1990.

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Lutsik, E.A. Pattern of response in neurosecretory cells of the rat hypothalamic supraoptic nucleus to subiculum stimulation under water deprivation. Neurophysiology 22, 193–198 (1990). https://doi.org/10.1007/BF01052170

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  • DOI: https://doi.org/10.1007/BF01052170

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