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Coordination compounds and micro-organisms. Part 11. Inhibition of bacterial growth by some Werner complex anions of cobalt(III)

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Summary

The growth of strains ofE. coli is inhibited in the early stages by several complex anions of cobalt(III). All of these contain chelating (chel) dicarboxylate ligands (propane-1, 3-dioate, ethane-1, 2-dioate, or carbonate)e.g. K3[Co(mal)3]3H2O where mal denotes the dianion of propane-1, 3-dioic acid, but most of them also contain unidentate pyridines,e.g. K[Co(chel)2(Rpy)2]nH2O. Among the most active arecis- andtrans-K[Co(mal)2(py)2] hydrates. The effects are distinct from those known for compounds of platinum,e.g. cis-[Pt(NH3)2Cl2] and rhodium,e.g. trans-[Rh(C5H5N)4Cl2]Cl·6H2O.

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References

  1. This paper is taken, in part, from the Ph.D. thesis of A.Y.A.M. (University of Wales, Cardiff, 1982) entitled “The Chemistry and the Bacterial Activities of some Compounds of Rhodium(III) and Cobalt(III)”: earlier Parts in this present series are: Part 1; R. J. Bromfield, R. H. Dainty, R. D. Gillard and B. T. Heaton,Nature,223, 735 (1969); Part 2; R. D. Gillard and C. Thorpe,Chem. Comm.,997, (1970); Part 3; R. D. Gillard,Record Chem. Progress,32, 17 (1971); Part 4; R. D. Gillard, J. R. Lyons and C. Thorpe,J. Chem. Soc. (Dalton), 1584 (1972); Part 5; L. S. Dollimore, R. D. Gillard, I.H. Mather,J. Chem. Soc. (Dalton), 518 (1974); Part 6; L. S. Dollimore, I. H. Mather and R. D. Gillard,Canadian J. Microbiol.,20, 1748 (1974); Part 7; R. D. Gillard, K. Harrison and I. H. Mather in “Platinum coordination Complexes in Cancer Chemotherapy” ed. T. A. Connors and J. A. Roberts, Springer Verlag 1974; Part 8; C. T. Thorpe and R. D. Gillard,Biochim Biophys. Acta,392, 175 (1975); Part 9; R. D. Gillard,Acta Chim. Acad. Sci. Hung.,47, 107 (1977); Part 10; R. D. Gillard, Abstract A8, Int. Conf. Chem. Platinum Metals, Royal Society of Chemistry, Bristol (UK) 1981.

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Author notes

  1. Ahmed Y. Ali-Mohamed

    Present address: University of Bahrain, P.O. Box 1082, Bahrain

  2. D. E. Hughes

    Present address: Middle Farm Villa, The Green, NN9 6AI, Chelveston, Northants, UK

Authors and Affiliations

  1. School of Chemistry and Applied Chemistry, University of Wales College of Cardiff, P.O. Box 912, CF1 3TB, Cardiff, UK

    Ahmed Y. Ali-Mohamed & R. D. Gillard

  2. Department of Microbiology, University College, P.O. Box 78, CF1 1XL, Cardiff, UK

    D. E. Hughes

Authors
  1. Ahmed Y. Ali-Mohamed
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  2. R. D. Gillard
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  3. D. E. Hughes
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Ali-Mohamed, A.Y., Gillard, R.D. & Hughes, D.E. Coordination compounds and micro-organisms. Part 11. Inhibition of bacterial growth by some Werner complex anions of cobalt(III). Transition Met Chem 14, 185–189 (1989). https://doi.org/10.1007/BF01043791

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