Summary
An adaptive algorithm for on-line kL-a estimation was developed. The accuracy of on-line kLa estimation was evaluated by means of digital and analog simulation. Simple difference schema developed on the basis of algorithm may be easily applicable in microcomputer-coupled fermentations.
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Votruba, J., Guthke, R. On line estimation of a fermenter aeration capacity (kLa) by a computer and dissolved oxygen probe. Biotechnol Lett 7, 267–272 (1985). https://doi.org/10.1007/BF01042375
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DOI: https://doi.org/10.1007/BF01042375