Summary
Four serum proteinase inhibitors, α1-macroglobulin, α1-proteinase inhibitor, α1-inhibitor3 and α1-acute phase macroglobulin, were localized in rat liver by immunofluorescent techniques. α1-Macroglobulin was observed predominantly in the sinusoids and α1-inhibitor3 in hepatocytes. In contrast, α1-proteinase inhibitor was localized in two sites, sinusoids and parenchymal cells. The fourth inhibitor tested, α2-acute phase macroglobulin, was barely detectable in normal liver. However, some appeared to be present in the extrahepatocyte space.
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Stauber, W., Fritz, V., Esnard, F. et al. Immunofluorescent localization of four serum proteinase inhibitors in normal rat liver. Histochem J 15, 161–166 (1983). https://doi.org/10.1007/BF01042284
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DOI: https://doi.org/10.1007/BF01042284