Abstract
In the dinoflagellateGonyaulax polyedra bioluminescence was investigated in constant darkness. Light emission was stimulated considerably and specifically by the biogenic smines epinephrine, 5-methoxytryptamine, and kynuramine. Various analogues and motabolites of these substances, such as norepinephrine, isoproterenol, phenylephrine, synephrine, metanephrine isoproterenol, phenylephrine, synephrine, metanephrine dopamine, 3,4-dihydroxymandelic and 3-methoxy hydroxymandelic acids, serotonin, N-acetylserotonin, melatonin, 5-hydroxytryptophol, 5-methoxytryptophol, kynurenine, 4-hydroxyquinoline, 3-hydroxyanthrani ic, and quinolinic acids were much less effective. Strong enhancement of bioluminescence, in the range of those obtained with the three stimulatory biogenic amines was also observed after administration of several compeunds acting as MAO inhibitors in mammalian systems, in particular, pargyline, amitriptyline,p-benzoquinone, tranylcypromine, harmaline, and noreleagnine. The responsiveness of cells towards epinephrine, 5-methoxytryptamine, kynuramine, amitriptyline,p-benzoquinone, and noreleagnine varied considerably within the circadian cycle, with the highest stimulations obtained during subjective night. These rhythms can be only partially explained by periodic bioluminescence capacity, and seem to comprise a cyclicity in the sensitivity of cells to the compounds mentioned.
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References
Arendt J (1986) Role of the pineal gland in seasonal reproduction function in mammals. Oxford Rev Reprod Biol 8:266–320
Balzer I, Hardeland R (1989a) Structural specificity of catecholamine action in the dinoflagellate,Gonyaulax polyedra. Comp Biochem Physiol 92C:297–300
Balzer I, Hardeland R (1989b) Action of kynuramine in a dimoflagellate: stimulation of bioluminescence inGonyoulax polyedra. Comp Biochem Physiol 94C:129–132
Balzer I, Hardeland R (1991) Stimulation of bioluminescence by 5-methoxylated indoleamines in the dinoflagellateConyaulax polyedra. Comp Biochem Physiol C, in press
Balzer I, Pöggeler B, Hardeland R (1989) Indoleamines in the cireadian organization onGonyaulax: evidence for presence and effects on bioluminescence. J Interdiscipl Cycle Res 20:169
Balzer I, Pöggeler B, Hardeland R (1990). Methoxylated indoleamines in the dinoflagellateGonyaulax polyedro: presence stimulation of bioluminescence and cireadian variations in responsiveness. Eur J Cell Biol 51 (Suppl 30):52
Behrmann G (1989) Die Rolle des Metabolismus der ronatischen Aminosäure Tryptophan beiGonyaulax polyedra. Diploma Thesis, University of Göttingen.
Czaba G (1981) Ontogeny and phylogeny of hormone receptors. In: Wolsky A, Carlson BM, Chen PS, Dettaff TA, Reverberi G, Scandalios JG (eds) Monographs in developmental biology, vol 15. Karger, Basel München Paris London New York Sydney, pp 1–169
Dunlap JC, Taylor W, Hastings JW (1981) The control and expression of bioluminescence in dinoflagellates. In: Nelason KH (ed) Bioluminescence: Current perspectives. Burgess, Minneapolis, pp 108–124
Hardeland R (1980) Effects of catecholamines on bioluminescence inGonyculax polyedra (Dinoflagellata). Comp Biochem Physiol 66C:53–58
Hasting JW, Krasnow R (1981) Temporal regulation in the individualGonyaulax cell. In: Schweiger HG (ed) International cell biology 1980–1981 Springer, Berlin Heidelberg New York, pp 815–822.
Hoffmann B, Hardeland R (1985) Membrane fluidization by propranolol, tetracaine and 1-aminoadamantane in the dinoflagelate,Gonyaulax polyedra. Comp Biochem Physiol 81C:39–43
Koella WP (1984a) Serotonin and sleep. In: Koella WP, Rüther E, Schulz H (eds) Sleep '84. Fischer, Stuttgart New York, pp 6–10.
Koella WP (1984b) Neurotransmitters and sleep — A synthesis. In: Koella WP, Rüther E, Schulz H (eds), Sleep '84, Fischer, Stuttgart New York, pp. 28–39
Krasnow R, Dunlap J, Taylor W, Hastings JW, Vetterling W, Haas E (1981) Measurements ofGonyaulax bioluminescence, including that of single cells. In: Nealson KH (ed) Bioluminescence: Current perspectives. Burgess, Minneapolis, pp 52–63
Monti JM (1984) Norepinephrine: its role in sleep and waking. In: Koella WP, Rüther E, Schulz H (eds) Sleep '84. Fischer, Stuttgart New York, pp 11–13.
Pöggeler B, Balzer I, Fischer J, Behrmann G, Hardeland R (1989) A role of melatonin in dinoflagellates? Acta Endocrinol (Copenhagen) 120, (Suppl 1):97
Reiter RJ (1980) The pineal and its hormones in the control of reproduction in mammals. Endocrinol Rev 1:109–131
Reiter RJ (1985) Action spectra, dose-response relationships, and temporal aspects of light's effects on the pineal gland. Ann NY Acad Sci 453:215–230
Tamarkin L, Baird CJ, Almeida OFX (1985) Melatonin. A coordinative signal for mammalian reproduction? Science 227:714–720
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Balzer, I., hardeland, R. Circadian rhythmicity in the stimulation of bioluminescence by biogenic amines and MAO inhibitors inGonyaulax polyedra . Int J Biometeorol 34, 231–234 (1991). https://doi.org/10.1007/BF01041834
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DOI: https://doi.org/10.1007/BF01041834