Summary
Washed-cell suspensions of cyclohexanol-grownAcinetobacter sp. NCIB 9871 have been shown to promote regio- and stereo-selective reduction of (±)-camphorquinone to yield two chiral diastereoisomericexo-hydroxyketones.
Similar content being viewed by others
References
Brooks, D.W., Mazdiyasni, H. and Sallay, P. (1985).J. Org. Chem., 50, 3411–3414.
Dale, J.A., Dull, D.L. and Mosher, H.S. (1969).J. Org. Chem., 34, 2543–2549.
Jones, J.B. (1986).Tetrahedron, 42, 3351–3403.
Levitt, M.S., Newton, R.F., Roberts, S.M. and Willetts, A.J. (1990a).J. Chem. Soc., Chem. Commun., 619–620.
Levitt, M., Sandey, H. and Willetts, A.J. (1990b).Biotechnol. Lett., 12, 197–200.
Nakazaki, M., Chikamatsu, H. and Asao, M. (1981a).J. Org. Chem., 46, 1147–1151.
Nakazaki, M., Chikamatsu, H., Nishio, M. and Murakami, H. (1981b).J. Org. Chem., 46, 1151–1156.
Pfrunder, B. and Tamm, C. (1969).Helv. Chim. Acta, 52, 1636–1642.
Rupe, R. and Müller, F. (1941).Helv. Chim. Acta, 24, 265E–282E.
Servi, S. (1990).Synthesis, 1–25.
Thoren, S. (1970).Acta Chem. Scand., 24, 93–98.
Yanai, M., Sugai, T. and Mori, K. (1985).Agric. Biol. Chem., 49, 2373–2377.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rebolledo, F., Roberts, S.M. & Willetts, A.J. Biotransformation of cycloalkanediones by microorganisms; Stereoselective reduction of (±)-camphorquinone. Biotechnol Lett 13, 245–248 (1991). https://doi.org/10.1007/BF01041478
Issue Date:
DOI: https://doi.org/10.1007/BF01041478