Summary
When passaging phage T7 and SAMase-negative T3 mutants betweenE. coli strains with identical (EcoB) or without (EcoO) DNA host specificity, phenotypically a host-controlled modification and restriction is observed. This phenomenon is not due to “classical” modification and restriction of the bacteriophage DNA but depends on the reversibly altered adsorption capacity of the phages on the different host strains.
References
Adams, M.H.: Bacteriophages. New York-London: Interscience Publ. 1959
Arber, W.: DNA modification and restriction. In: Progress in nucleic acid research and molecular biology (Cohn, W.E., ed.), Vol. 14, pp. 1–37. New York-San Francisco-London: Academic Press 1974
Arber, W., Yuan, R., Bickle, T.A.: Strain-specific modification and restriction of DNA in bacteria. In: Post-synthetic modification of macromolecules (Antoni, F. and Farago, A. eds.), pp. 3–22. Amsterdam-London: North Holland/American Elsevier 1975
Boyer, H.W.: DNA restriction and modification mechanisms in bacteria. Ann. Rev. Microbiol.25, 153–176 (1971)
Boyer, H.W.: Restriction and modification of DNA: enzymes and substrates. Fed. Proc.33, 1125–1127 (1974)
Clowes, R.C., Hayes, W.: Experiments in microbial genetics. Oxford-Edinburgh: Blackwell Sci. Publ. 1968
Demerec, M., Fano, U.: Bacteriophage-resistant mutants inE. coli. Genetics30, 119–136 (1945)
Eskridge, R.W., Weinfeld, H., Paigen, K.: Susceptibility of different coliphage genomes to host-controlled variation. J. Bact.93, 835–844 (1967)
Hancock, R.E.W., Reeves, P.: Bacteriophage resistance inE. coli K12: general pattern of resistance. J. Bact.121, 983–993 (1975)
Hausmann, R.L., Almeida-Magalhaes, E.P., Araujo, C.: Isolation and characterization of hybrids between bacteriophages T3 and T7. Anais Microbiol.9, 511–526 (1961)
Klagsbrun, M., Furano, A.V.: Methylated amino acids in the proteins of bacterial and mammalian cells. Arch. Biochem. Biophys.169, 529–539 (1975)
Krüger, D.H., Hansen, S., Presber, W.: Host-controlled modification and restriction of bacteriophage T7 by variousE. coli B strainsin vivo. Z. allg. Mikrobiol.16, 73–76 (1976)
Krüger, D.H., Schroeder, C., Hansen, S., Rosenthal, H.A.: Active protection by bacteriophage T3 and T7 againstE. coli B- and K-specific restriction of their DNA. Molec. gen. Genet.153, 99–106 (1977)
Lindberg, A.A.: Bacteriophage receptors. Ann. Rev. Microbiol.27, 205–241 (1973)
Luria, S.E.: Host-induced modification of viruses. Cold Spr. Harb. Symp. quant. Biol.18, 237–244 (1953)
Meselson, M., Yuan, R., Heywood, J.: Restriction and modification of DNA. Ann. Rev. Biochem.41, 447–466 (1972)
Wood, W.B.: Host specificity of DNA produced byE. coli: Bacterial mutations affecting the restriction and modification of DNA. J. molec. Biol.16, 118–133 (1966)
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Communicated by W. Arber
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Krüger, D.H., Hansen, S., Schroeder, C. et al. Host-dependent modification of bacteriophage T7 and SAMase-negative T3 derivatives affecting their adsorption ability. Molec. Gen. Genet. 153, 107–110 (1977). https://doi.org/10.1007/BF01036002
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DOI: https://doi.org/10.1007/BF01036002