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It has been shown that the closure of the pyrroline ring with simultaneous N-dealkylation observed previously for the reactions of 2- and 4-chloro-3-(β-chloroethyl)pyrimidines with secondary amines has a general nature and is suitable for the synthesis of 5,7-diazaindoline derivatives from 4-chloro-5-(β-chloroethyl)pyrimidines. Features of the structure of 5,7-diazaindoline systems connected with the electron-accepting properties of the nitrogen atom of the pyrimidine nucleus are discussed.
KeywordsNitrogen Organic Chemistry Nitrogen Atom Pyrimidine General Nature
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