Chemistry of Heterocyclic Compounds

, Volume 5, Issue 1, pp 108–111 | Cite as

5-Substituted pyrimidine derivatives

II. Synthesis of 5, 6-dihydropyrrolo[2,3-d]pyrimidines (5,7-diazaindolines)
  • K. A. Chkhikvadze
  • N. I. Koretskaya
  • N. S. Rodnyanskaya
  • O. Yu. Magidson


The properties and reactivities of 4-hydroxy- and 2,4-dihydroxy-5-(β-hydroxyethyl)pyrimidines and of the products of their transformations have been studied. 4-Chloro- and 2,4-dichloro-5-(β-chloroethyl)pyrimidines have been obtained. A number of 4-alkyl(aryl)amino-5-(β-chloroethyl)pyrimidines have been synthesized, and they have been converted into derivatives of 5,6-dihydropyrrolo[2,3-d]pyrimidine.


Organic Chemistry Pyrimidine Pyrimidine Derivative 
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Copyright information

© Consultants Bureau 1971

Authors and Affiliations

  • K. A. Chkhikvadze
    • 1
  • N. I. Koretskaya
    • 1
  • N. S. Rodnyanskaya
    • 1
  • O. Yu. Magidson
    • 1
  1. 1.Ordzhonikidze All-Union Chemical and Pharmaceutical Scientific-Research InstituteMoscow

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