Chemistry of Heterocyclic Compounds

, Volume 5, Issue 1, pp 73–74 | Cite as

Indole derivatives

XXXIV. Synthesis of 2-substituted 4-(3'-indolyl)thiazoles
  • Yu. I. Smushkevich
  • Ts. M. Babueva
  • N. N. Suvorov
Article

Abstract

The reaction of 3-chloroacetylindole (I) with thioformamide, thiourea, and ammonium dithiocarbamate has given, respectively, 4-(3'-indolyl)thiazole (II), 2-amino-4-(3'-indolyl)thiazole (III), and 4-(3'-indolyl)-2-mercaptothiazole (V), identified by the preparation of derivatives and UV and IR spectra.

Keywords

Ammonium Organic Chemistry Indole Thiourea Thiazole 

References

  1. 1.
    N. N. Suvorov, V. P. Gorbunova, and K. F. Turchin, KhGS [Chemistry of Heterocyclic Compounds],4, 1029, 1968.Google Scholar
  2. 2.
    K. Canapathi and A. Venkataraman, Proc. Indian Acad. Sci.,22A, 363, 1945.Google Scholar
  3. 3.
    Heterocyclic Compounds, Vol. 5 [Russian translation], IL, Moscow, p. 448, 1961.Google Scholar
  4. 4.
    A. Gillem and E. Stern, An Introduction to Electronic Absorption Spectroscopy in Organic Chemistry [Russian translation], IL, Moscow, p. 317, 1957.Google Scholar
  5. 5.
    C. M. Badger and N. Kowanco, J. Chem. Soc., 1652, 1957.Google Scholar
  6. 6.
    C. D. Hurd and B. Rudner, J. Am. Chem. Soc.,73, 5157, 1951.Google Scholar
  7. 7.
    H. Hauptman and W. F. Walter, Chem. Rev.,62, 347, 1962.Google Scholar
  8. 8.
    S. G. Bogomolov, Yu. N. Sheinker, and I. Ya. Postovskii, DAN,93, 277, 1953.Google Scholar
  9. 9.
    P. L. Julian and B. M. Sturgis, J. Am. Chem. Soc.,57, 1126, 1935.Google Scholar
  10. 10.
    A. Pavlic and H. Adkins, J. Am. Chem. Soc.,68, 1471, 1946.Google Scholar

Copyright information

© Consultants Bureau 1971

Authors and Affiliations

  • Yu. I. Smushkevich
    • 1
  • Ts. M. Babueva
    • 1
  • N. N. Suvorov
    • 1
  1. 1.Mendeleev Chemical and Technological InstituteMoscow

Personalised recommendations