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An adaptive on-line control feed rate system in a laboratory scale bakers yeast process

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Summary

A new control policy for the on-line optimization of the nutrient supply in bakers yeast process is proposed. A feed rate corresponding to minimal substrate uptake time was shown to be optimal for cell yield and specific growth rate. Cultivation results of baker's yeast are presented.

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Abbreviations

c:

glucose concentration in wort (mol.l−1)

C:

total glucose used (mol)

ce :

ethanol concentration in wort (mg.l−1)

cp :

glucose concentration in fresh medium (mol.l−1)

dt/dc:

glucose consumption time (sec.mol−1)

F:

substrate feed rate (litre.hr−1)

qc :

glucose uptake rate (mol.hr−1)

Qc :

specific glucose uptake rate (moll.g−1.hr−1)

qO2 :

oxygen uptake rate (mol.hr−1)

QO2 :

specific oxygen uptake rate (mol.g−1.hr−1)

rx :

productivity (g.l−1.hr−1)

t:

time (hr)

x:

biomass concentration (g.l−1)

X:

total biomass (g)

Yx/c :

cell yield (g.g−1): (g.mol−1)

Yo/c :

consumed oxygen to glucose ratio (mol.mol−1)

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Miskiewicz, T., Miszczak, W. An adaptive on-line control feed rate system in a laboratory scale bakers yeast process. Biotechnol Lett 7, 365–368 (1985). https://doi.org/10.1007/BF01030289

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  • DOI: https://doi.org/10.1007/BF01030289

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