Summary
A new control policy for the on-line optimization of the nutrient supply in bakers yeast process is proposed. A feed rate corresponding to minimal substrate uptake time was shown to be optimal for cell yield and specific growth rate. Cultivation results of baker's yeast are presented.
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Abbreviations
- c:
-
glucose concentration in wort (mol.l−1)
- C:
-
total glucose used (mol)
- ce :
-
ethanol concentration in wort (mg.l−1)
- cp :
-
glucose concentration in fresh medium (mol.l−1)
- dt/dc:
-
glucose consumption time (sec.mol−1)
- F:
-
substrate feed rate (litre.hr−1)
- qc :
-
glucose uptake rate (mol.hr−1)
- Qc :
-
specific glucose uptake rate (moll.g−1.hr−1)
- qO2 :
-
oxygen uptake rate (mol.hr−1)
- QO2 :
-
specific oxygen uptake rate (mol.g−1.hr−1)
- rx :
-
productivity (g.l−1.hr−1)
- t:
-
time (hr)
- x:
-
biomass concentration (g.l−1)
- X:
-
total biomass (g)
- Yx/c :
-
cell yield (g.g−1): (g.mol−1)
- Yo/c :
-
consumed oxygen to glucose ratio (mol.mol−1)
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Miskiewicz, T., Miszczak, W. An adaptive on-line control feed rate system in a laboratory scale bakers yeast process. Biotechnol Lett 7, 365–368 (1985). https://doi.org/10.1007/BF01030289
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DOI: https://doi.org/10.1007/BF01030289