Skip to main content
Log in

Temperature as an enantioselective parameter in enzymatic resolutions of racemic mixtures

  • Published:
Biotechnology Letters Aims and scope Submit manuscript

Summary

In the field of enhancement of the enantiomeric excess, the effect of temperature on the enantiomeric ratio, E, was investigated in lipase catalysed hydrolysis and transesterification. It was found that the equation (E1)T1=(E2)T2 correlated well with the experimental data obtained.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Barton, M.J., Hamman, J.P., Fichter, K.C. and Calton, G.J. (1990)Enzyme Microb. Technol.,12, 577–583.

    Google Scholar 

  • Boutelje, J., Hjalmarsson, M., Hult, K., Lindbäck, M. and Norin, T. (1988)Bioorg. Chem.,16, 364–375.

    Google Scholar 

  • Chen, C.-S., Fujimoto, Y., Girdaukas, G. and Sih, C.J. (1982)J. Am. Chem. Soc.,104, 7294–7299.

    Google Scholar 

  • Chen, C.-S., Wu, S-H. Girdaukas, G. and Sih, C.J. (1987)J. Am. Chem. Soc.,109, 2812–2817.

    Google Scholar 

  • Chen, S.-S. and Sih, C.J. (1989)Angew. Chem. Int. Ed. Engl.,28, 695–707.

    Google Scholar 

  • Fersht, A. (1985) Enzyme structure and mechanism. 2nd ed., W.H. Freeman and Co., New York.

    Google Scholar 

  • König, W.A., Francke, W. and Benecke, I. (1982)J. Chromatogr.,239, 227–231.

    Google Scholar 

  • Lam, L.K.P., Hui, R.A.H.F. and Jones, J.B. (1986)J. Org. Chem.,51, 2047–2050.

    Google Scholar 

  • Otto, P.P.H.L. (1990)Chem. Biochem. Eng. Q,4(3), 137–149.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Holmberg, E., Hult, K. Temperature as an enantioselective parameter in enzymatic resolutions of racemic mixtures. Biotechnol Lett 13, 323–326 (1991). https://doi.org/10.1007/BF01027676

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01027676

Keywords

Navigation