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Enhancement of catalytic activity of porcine pancreatic lipase by reductive alkylation

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Summary

Chemical modification by reductive alkylation of porcine pancreatic lipase with n-butyraldehyde, isobutyraldehyde and acetone resulted in about 50% increase in theV max of the enzyme.E act was reduced by about 40% by this modification. Both hydrolytic and interesterification activities were enhanced without affecting the 1,3-specificity of the enzyme.

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Article Open access 02 December 2021

Baoxin Zhang, Dilver Peña Fuentes & Armin Börner

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Authors and Affiliations

  1. Regional Research Laboratory (CSIR), 500 007, Hyderabad, India

    T. N. B. Kaimal & M. Saroja

Authors
  1. T. N. B. Kaimal
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  2. M. Saroja
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Kaimal, T.N.B., Saroja, M. Enhancement of catalytic activity of porcine pancreatic lipase by reductive alkylation. Biotechnol Lett 11, 31–36 (1989). https://doi.org/10.1007/BF01026782

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  • DOI: https://doi.org/10.1007/BF01026782

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