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Selective production of phenylalanine from phenylpyruvate using growing cells ofCorynebacterium glutamicum

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Summary

Phenylalanine was produced from phenylpyruvate by growing cells of a mutant strain ofCorynebacterium glutamicum over-producing valine. A defined medium was used to minimize the accumulation of valine. The maximum phenylalanine concentration achieved was 44.5 mM (7.5 g/l) with a phenylpyruvate molar conversion of 75%.

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Authors and Affiliations

  1. Department of Chemical Engineering, Massachusetts Institute of Technology, 02139, Cambridge, MA

    E. Bulot & C. L. Cooney

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  1. E. Bulot
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  2. C. L. Cooney
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Bulot, E., Cooney, C.L. Selective production of phenylalanine from phenylpyruvate using growing cells ofCorynebacterium glutamicum . Biotechnol Lett 7, 93–97 (1985). https://doi.org/10.1007/BF01026675

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  • DOI: https://doi.org/10.1007/BF01026675

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