Summary
Released free cells of immobilized growing acetic acid bacteria during 460 days of long run in a bioreactor were increased at a high dilution rate. This was interpreted by the facts that newly released cells from the carrier showed a synchronized growth and had extremely high growth rates and a respiratory activity. The suitable leakage is effective for high productivity of the immobilized growing cell culture.
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Mori, A., Matsumoto, N. & Imai, C. Growth behavior of immobilized acetic acid bacteria. Biotechnol Lett 11, 183–188 (1989). https://doi.org/10.1007/BF01026053
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DOI: https://doi.org/10.1007/BF01026053